红细胞储存损伤研究进展

发布时间：2018-03-17 15:06

本文选题：红细胞　切入点：储存损伤　出处：《中国输血杂志》2017年09期 　论文类型：期刊论文

【摘要】：本文回顾了近年来红细胞储存损伤的国内外文献,从储存红细胞的理化性状、生物代谢、献血者个体差异、血袋与保存液不同、白细胞去除等红细胞储存损伤的相关影响因素,介绍了红细胞储存损伤的最新研究进展,讨论了红细胞储存损伤热点问题"新""老"红细胞有无差异,并指出目前研究存在的根本问题是没有1个统一的标准来定义"新""老"红细胞。最后提出了研究红细胞储存损伤的重点应该放在红细胞的疗效上,而不是单纯的延长保存时间等,为红细胞储存与相关疗效的研究提供了一定指导意义。
[Abstract]:In this paper, the domestic and foreign literatures on erythrocyte storage injury were reviewed. The related factors of red blood cell storage damage, such as physical and chemical properties, biological metabolism, individual differences of blood donors, different blood bags from preservation solution, leukocyte removal and so on, were reviewed. This paper introduces the latest research progress of erythrocyte storage injury, and discusses whether there is any difference between new and old red blood cells, which is a hot issue of erythrocyte storage injury. It is pointed out that there is no unified standard to define "new" and "old" red blood cells. Finally, the emphasis of research on erythrocyte storage damage should be put on the curative effect of red blood cells. Instead of simply prolonging the storage time, it provides guidance for the study of erythrocyte storage and related therapeutic effects.
【作者单位】：第二军医大学长海医院输血科;解放军昆明总医院;
【分类号】：R977.8

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