外科预防性应用抗菌药物的干预效果评价

发布时间：2018-03-25 15:24

  本文选题：外科　切入点：抗菌药物　出处：《中华医院感染学杂志》2015年14期

【摘要】：目的了解干预前后外科各科室抗菌药物临床应用情况,评价干预措施效果,以提高抗菌药物合理使用率。方法采用流行病学调查方法,将2010年7-12月2 508份出院病历作为干预前组,2011年7-12月2 890份出院病历作为干预后组,比较干预前后两组患者抗菌药物的使用率。结果干预前抗菌药物使用率为80.9%、干预后为71.8%,二者差异有统计学意义(χ2=127.8,P0.05);围术期抗菌药物规范执行率干预前为96.2%、干预后为98.6%,二者差异有统计学意义(χ2=11.4,P0.05);Ⅰ类切口手术预防性抗菌药物使用率干预前为81.5%、干预后为63.6%,二者差异有统计学意义(χ2=14.6,P0.05)。结论采取的综合性干预措施有效降低了外科各科室抗菌药物的使用率,提高了围术期抗菌药物的规范执行率,降低了Ⅰ类切口手术预防性抗菌药物使用率。
[Abstract]:Objective to investigate the clinical application of antimicrobial drugs in surgical departments before and after intervention, and evaluate the effect of intervention measures to improve the rational utilization rate of antimicrobial agents. 2,508 discharge records from July to December 2010 were taken as pre-intervention group, and 2,890 discharge medical records from July to December 2011 were taken as post-intervention group. Results the utilization rate of antimicrobial agents before and after intervention was 80.9 and 71.8, respectively (蠂 ~ 2 / 127.8 / P 0.05), and the standard execution rate of antimicrobial drugs in perioperative period was 96.2g / g, respectively, compared with that before and after the intervention (蠂 ~ (2) 127.8p 0.05). 98.6, the difference between them was statistically significant (蠂 ~ 2 + 11.4m, P 0.05); the rate of utilization of prophylactic antimicrobial agents in type 鈪，

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