临床药师干预清洁手术围术期预防应用抗菌药物的对比分析

发布时间：2018-04-09 17:14

本文选题：临床药师　切入点：抗菌药物　出处：《中华医院感染学杂志》2015年03期

【摘要】：目的评价临床药师干预清洁手术患者围手术期抗菌药物使用的效果,以提高合理用药水平。方法分别抽取医院2011年7-12月(干预前)和2012年7-12月(干预后)骨科清洁手术出院患者病历各150份,对围手术期预防性应用抗菌药物的合理性进行比较,采用Excel进行数据录入和处理,应用SPSS15.0软件进行统计分析。结果干预前有138例患者在围手术期预防性应用抗菌药物,经临床药师干预后,有70例患者预防性应用抗菌药物,抗菌药物使用率由92.00%降至46.67%,联合用药比例由7.25%降至0,品种选择合理率由23.91%升至97.14%,用药时机合理率由56.52%升至100.00%,用药疗程合理率由37.68%升至81.43%,总药品费用占住院总费用的比例由27.32%降至23.44%,抗菌药物总费用占总药品费用的比例由14.26%降至1.68%,患者人均住院天数下降1.25d。结论临床药师对围术期预防应用抗菌药物进行干预的方法是可行且有效,能提高医院抗菌药物的合理使用水平,减少患者的住院时间和住院费用,对临床安全、有效、经济的应用抗菌药物起到了积极作用。
[Abstract]:Objective to evaluate the effect of clinical pharmacists on the perioperative use of antimicrobial agents in clean surgery patients and to improve the level of rational use of antibiotics.Methods 150 medical records of patients discharged from orthopedic clean surgery in July to December 2011 (before intervention) and 150 cases from orthopedic department (after intervention) were collected respectively. The rationality of prophylactic use of antimicrobial agents in perioperative period was compared.Excel is used for data entry and processing, and SPSS15.0 software is used for statistical analysis.Results before intervention, 138 patients were given prophylactic use of antimicrobial agents during perioperative period, and 70 patients received prophylactic use of antimicrobial agents after intervention by clinical pharmacists.The utilization rate of antimicrobial agents decreased from 92.00% to 46.67um, the proportion of combined drug use decreased from 7.25% to 0, the reasonable rate of selection of varieties increased from 23.91% to 97.14. The rational rate of timing of use increased from 56.52% to 100.000.The reasonable rate of course of treatment increased from 37.68% to 81.43. The total cost of drugs accounted for the total cost of hospitalization.The proportion of total cost of antimicrobial drugs in total drug cost decreased from 14.26% to 1.68, and the days of hospitalization per patient decreased by 1.25 days.Conclusion it is feasible and effective for clinical pharmacists to intervene in perioperative prophylactic use of antimicrobial agents, which can improve the level of rational use of antimicrobial agents in hospitals, reduce the hospitalization time and hospital expenses of patients, and be safe and effective in clinical practice.Economic use of antimicrobial agents played a positive role.
【作者单位】：咸阳市中心医院药剂科;陕西中医学院病原生物及检验学教研室;
【基金】：陕西省科技厅自然科学基金资助项目(2012JM4016)
【分类号】：R95

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