胰腺疾病药物专利申请态势分析

发布时间：2018-04-11 16:45

本文选题：胰腺疾病 + 专利分析　；参考：《山西医科大学》2017年硕士论文

【摘要】：目的:胰腺疾病发病率逐年增高,患病人群逐年庞大,严重威胁公众健康。通过对其药物专利信息进行挖掘与解读,可以了解研发动态,掌握国际竞争态势,为我国药物研发和专利布局提供重要参考。方法:本文主要使用了专利分析法,并结合药学专业知识,对胰腺疾病药物专利国内外申请态势进行了系统分析。专利分析法包括定性分析与定量分析,通过对专利申请量、申请区域、申请技术领域、申请学科领域、申请人、发明人等指标的定量分析与对专利法律状态指标的定性分析。结果:1.国际该领域的药物研发处于平稳递减时期,技术趋于成熟;化学、药理学与药学、工程学、计算机科学等不同学科领域之间正在相互渗透;美国、日本、中国及部分欧洲国家是主要申请区域;通用抗炎药物与癌症治疗是主要技术领域;美国默克集团、日本武田药品工业株式会社及德国勃林格殷格翰公司作为技术引领者,拥有大量专利,领先优势明显,近年来专利数量增长迅速,技术研发逐步增强;美国默克集团、诺华公司、强生公司以及辉瑞公司具有较强的合作能力。2.国内该领域的药物研发处于快速增长阶段,市场广阔;处于实质审查法律状态中的专利数量占到三分之一,新技术发展潜力巨大;山东省、江苏省、上海市等是主要申请区域;传统草药的研发与利用是重点关注的技术领域;广东东阳光药业有限公司以及南京大学、中国人民解放军第二军医大学等高校掌握大量专利技术,吴俊华、张英俊团队、卞永兴等是该领域核心发明人。结论:1.国际专利申请数量回缓,国内专利申请数量激增,现阶段,相关制药企业及研发机构应注重知识积累与沉淀,提升自身科研素质,充分利用现有知识,掌握核心技术,寻找潜在合作伙伴,同时尽早跑马圈地,抢占市场。2.教育水平与经济实力影响专利申请,对于科研产出高的地区,应鼓励该地区制药企业、科研单位走出去,积极寻找与美国、日本等国家的合作机会,取长补短;同时,加快科技转化,使专利技术更早地改善胰腺疾病患者的治疗水平。3.通用抗炎药物、一般癌症治疗及传统草药的开发与利用是主要技术方向,在胰腺疾病治疗药物研发中起着重要的支撑作用,应在研发投入上稍有侧重,发展新技术,迅速占领市场,提升自身竞争力与影响力。4.制药企业以及高等院校是主要申请人,应促进合作,拓宽研究领域,加深研究深度,优化专利布局,提高整体的专利水平,获得共赢;同时,在不断的引进和消化的过程中,还应注意对我国自主知识产权的保护。
[Abstract]:Objective: the incidence of pancreatic diseases is increasing year by year and the number of people suffering from pancreatic diseases is increasing year by year, which is a serious threat to public health.By digging and interpreting the information of drug patent, we can understand the research and development trends, grasp the international competition situation, and provide an important reference for our country's drug research and development and patent layout.Methods: the patent analysis method was used in this paper, and the patent application situation at home and abroad for pancreatic diseases was systematically analyzed.Patent analysis includes qualitative analysis and quantitative analysis, through the quantitative analysis of patent application volume, application area, application technology field, application subject field, applicant, inventor and so on, and the qualitative analysis of patent legal status index.The result is 1: 1.International drug research and development in this field is in a period of steady decline, technology tends to mature; chemistry, pharmacology and pharmaceutical, engineering, computer science and other different disciplines are infiltrating each other; the United States, Japan,In recent years, the number of patents has increased rapidly, technology research and development has been gradually enhanced; Merck Group, Novartis, Johnson and Pfizer have strong cooperation ability.The domestic drug research and development in this field is in the stage of rapid growth, the market is broad, the number of patents in the legal state of substantive examination accounts for 1/3, the development potential of new technology is huge, Shandong Province, Jiangsu Province, Shanghai and so on are the main application areas;The research and development and utilization of traditional herbal medicines are the key technical fields; Guangdong Dongyang Pharmaceutical Co., Ltd., Nanjing University, the second military Medical University of the Chinese people's Liberation Army and other universities have a large number of patented technologies. Wu Junhua, Zhang Ching's team,Bian Yongxing and others are the core inventors in this field.Conclusion 1.The number of international patent applications has slowed down, and the number of domestic patent applications has increased sharply. At the present stage, relevant pharmaceutical enterprises and R & D institutions should pay attention to the accumulation and precipitation of knowledge, improve their own scientific research quality, fully utilize existing knowledge, and master core technologies.Looking for potential partners, while at the same time, as early as possible to seize the market. 2.The level of education and economic strength affect patent applications. For areas with high scientific research output, pharmaceutical enterprises and scientific research institutions in the region should be encouraged to go out and actively seek opportunities for cooperation with the United States, Japan, and other countries.Accelerate the transformation of science and technology, so that patent technology to improve the treatment of pancreatic disease patients. 3. 3.The development and utilization of general anti-inflammatory drugs, general cancer treatment and traditional herbs are the main technical directions. They play an important supporting role in the research and development of pancreatic disease treatment drugs, so we should put a little emphasis on the R & D investment and develop new technologies.Quickly occupy the market, enhance their competitiveness and influence. 4.Pharmaceutical enterprises and institutions of higher learning are the main applicants. They should promote cooperation, broaden research fields, deepen research depth, optimize patent layout, improve the overall patent level, and obtain win-win results. At the same time, in the process of continuously introducing and digesting,Attention should also be paid to the protection of independent intellectual property rights in China.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R975;G306

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