我院成人使用水合氯醛溶液的处方分析及制剂规格探讨

发布时间：2018-04-15 00:19

本文选题：水合氯醛溶液 + 医院制剂　；参考：《中国药师》2016年11期

【摘要】：目的:采样分析我院成人使用水合氯醛溶液的实际情况,探讨防止浪费或误服用药的措施,设置更加符合临床需求的水合氯醛自制制剂规格。方法:分析我院2015年7~12月所有18岁以上成年患者使用水合氯醛溶液的所有处方,对其使用科别、患者年龄、用途、使用剂量等情况进行统计和分析。结果:2015年7~12月我院18岁以上成年患者使用水合氯醛溶液的处方共计1 360张,使用规格均为30 ml,多用于神经科、神经外科的检查前睡眠诱导用;使用水合氯醛溶液的患者大多数是50岁(含50岁)以下的中青年患者;有94.85%的处方使用剂量为15 ml,98.97%的处方存在用量低于包装规格的现象,以及多余药液被误服的风险。结论:我院目前水合氯醛溶液的实际使用剂量明显小于药品的包装规格,存在误服过量的风险,故包装规格偏大,有必要改善包装规格,方便临床使用;药师在发药时需充分告知用法用量和注意事项,避免误服过量的风险。
[Abstract]:Objective: to sample and analyze the actual situation of adults using chloral hydrate solution in our hospital, to discuss the measures to prevent waste or misadministration of chloral hydrate solution, and to set up the homemade preparation of chloral hydrate which is more suitable for clinical requirement.Methods: all prescriptions of chloral hydrate solution for all adult patients over 18 years of age in our hospital from July to December 2015 were analyzed.Results: from July to December 2015, 1 360 prescriptions of chloral hydrate solution were used in adult patients over 18 years old in our hospital. The prescriptions were all 30 ml, which were mostly used for sleep induction before neurology and neurosurgery examination.Most of the patients who used chloral hydrate solution were under 50 years old (including 50 years old), 94.85% of the prescriptions with a dosage of 15 ml ~ 98.97% had the phenomenon of using less than the packing specification, and the risk of overdose being taken by mistake.Conclusion: the actual dosage of chloral hydrate solution in our hospital at present is obviously smaller than the packing specification of drug, and there is the risk of overdose, so the packing specification is too large, it is necessary to improve the packing specification and make it convenient for clinical use.Pharmacists should fully inform the usage and precautions when dispensing drugs to avoid the risk of overdose.
【作者单位】：中国医学科学院-北京协和医学院北京协和医院药剂科;
【分类号】：R95

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