三城市42家医院2012-2016年抗肿瘤药应用分析

发布时间：2018-04-20 20:59

本文选题：抗肿瘤药 + 销售金额　；参考：《中国药房》2017年26期

【摘要】：目的:分析北京、上海、成都三城市42家医院抗肿瘤药临床应用情况及趋势,为临床合理用药提供参考。方法:对北京、上海和成都三城市42家医院2012-2016年抗肿瘤药销售金额、用药频度(DDDs)等进行统计分析。结果:三城市抗肿瘤药总销售金额呈逐年上升趋势,北京销售金额在三城市中居首位,上海年均增长率最高。三城市5年抗肿瘤药销售金额排名中,免疫抑制剂他克莫司、吗替麦考酚酯均进入了各城市销售金额排名前10位。北京、上海和成都销售金额排名首位的药品分别为胸腺五肽、他克莫司和胸腺法新。抗肿瘤药各亚类中,北京、成都2012-2014年其他抗肿瘤药及辅助治疗药的销售金额均居首位,2015-2016年抗代谢药的销售金额居首位,且北京高于成都;上海2012-2016年均以抗代谢药销售金额居首位。三城市2012-2014年各抗肿瘤药亚类销售金额最高的是其他抗肿瘤及辅助治疗药,2015-2016年是抗代谢药。相关治疗药物中,免疫增强剂、免疫抑制剂和镇痛药的销售金额均排名靠前;DDDs前10名中,激素类抗肿瘤药最多,烷化剂仅环磷酰胺进入排名。结论:三城市抗肿瘤药销售金额增长趋势平稳;抗代谢药、激素类和植物来源的抗肿瘤药使用越来越多;分子靶向治疗药物有良好的应用前景。
[Abstract]:Objective: to analyze the clinical application and trend of antitumor drugs in 42 hospitals in Beijing, Shanghai and Chengdu. Methods: 42 hospitals in Beijing, Shanghai and Chengdu from 2012 to 2016 were statistically analyzed. Results: the total sales amount of antineoplastic drugs in the three cities was increasing year by year. Beijing ranked first in the three cities, and Shanghai had the highest average annual growth rate. In the five-year sales of antineoplastic drugs in the three cities, the immunosuppressant tacrolimus and metocophenolate ester were among the top 10 in each city. Beijing, Shanghai and Chengdu topped the list of drugs with thymosin, tacrolimus and thymoxacin, respectively. Among the subgroups of antitumor drugs, the sales amount of other antitumor drugs and adjuvant treatment drugs in Beijing and Chengdu in 2012-2014 was the first. In 2015-2016, the sales amount of anti-metabolites was the first, and Beijing was higher than Chengdu. Shanghai 2012-2016 annual sales of anti-metabolic drugs in the first place. Other antitumor and adjuvant drugs in 2015-2016 were among the three cities with the highest sales of each subclass of antitumor drugs in 2012-2014. Among the related drugs, the sales amount of immunoenhancer, immunosuppressant and analgesics were among the top 10 in DDDs, the hormone antitumor drugs were the most, and only cyclophosphamide was the only alkylating agent. Conclusion: the trend of sales of antitumor drugs in three cities is stable, the use of anti-metabolites, hormones and phytogenic antitumor drugs is increasing, and the molecular targeted therapy has a good application prospect.
【作者单位】：成都中医药大学药学院;四川省人民医院药学部;
【分类号】：R979.1

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