临床药师干预Ⅰ类切口手术抗菌药物预防性使用的效果评价

发布时间：2018-04-22 18:18

  本文选题：临床药师 + 干预　； 参考：《中国感染控制杂志》2016年04期

【摘要】：目的评价临床药师干预Ⅰ类切口手术围手术期抗菌药物预防性使用的效果。方法对某院2014年1—12月收治的1 398例Ⅰ类切口手术患者的临床资料进行回顾性分析,其中2014年1—6月收治的633例患者作为干预前组;2014年7—12月收治的765例患者作为干预后组(设置临床药师,加强对合理用药的管理与控制),比较干预前后患者围手术期预防性使用抗菌药物情况。结果干预前后两组围手术期患者抗菌药物预防性使用率分别为56.71%和28.37%,差异具有统计学意义(χ2=113.26,P0.05)。干预前、后两组患者抗菌药物品种选择合理率分别为60.45%、89.86%,给药时机合理率分别为49.58%、82.49%,预防性应用抗菌药物疗程≤24 h者分别为11.42%、29.95%,疗程24 h者分别为88.58%、70.05%,联合用药比率分别为10.31%、0,干预前后比较,差异均具有统计学意义(均P0.05)。干预前后两组患者Ⅰ类切口感染发病率分别为0.79%(5/633)、0.26%(2/765),差异无统计学意义(P=0.255)。结论通过临床药师对Ⅰ类切口手术围手术期抗菌药物预防性使用干预,其使用率显著下降,使该院抗菌药物管理工作更加规范化、科学化和制度化。
[Abstract]:Objective to evaluate the effect of clinical pharmacists on prophylactic use of antibiotics in perioperative period of type I incision operation. Methods the clinical data of 1,398 patients with type I incision operation in a hospital from January to December 2014 were retrospectively analyzed. 633 patients were treated as pre-intervention group from January to June 2014 and 765 patients from July to December 2014 as post-intervention group (setting up clinical pharmacists, To strengthen the management and control of rational drug use and compare the prophylactic use of antimicrobial agents in perioperative period before and after intervention. Results the prophylactic use rate of antimicrobial agents in the two groups was 56.71% and 28.37 respectively before and after the intervention. The difference was statistically significant (蠂 2 113.26 P 0.05). Before intervention, The rational rate of choice of antimicrobial drugs in the latter two groups were 60.45 and 89.86, the rational rates of timing of administration were 49.58 and 82.49, the courses of prophylactic use of antibiotics 鈮，

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