某“三甲”医院2012-2013年抗菌药物使用强度分析

发布时间：2018-04-27 15:15

本文选题：抗菌药物 + 限定日剂量　；参考：《中国药房》2015年02期

【摘要】：目的:为抗菌药物长效管理提供参考。方法:回顾性收集该院2012-2013年抗菌药物的使用数据,采用Excel 2003进行统计,以限定日剂量(DDD)为单位,计算抗菌药物的使用强度(AUD),并进行比较、分析。结果:该院AUD值控制较平稳,2012、2013年的AUD值分别为40.46、42.56 DDDs/(100人·d),虽较接近目标,但仍有一定距离。2013年有一半科室的AUD值较2012年升高,其中呼吸科、重症医学科、皮肤科、康复科及烧伤整形科的AUD值涨幅较大。AUD排前5位的抗菌药物种类保持不变,分别为青霉素类+酶抑制剂、第三代头孢菌素、喹诺酮类、第二代头孢菌素及青霉素类。AUD值排前20位的药物均为注射剂。2013年特殊使用级抗菌药物AUD值下降明显,而限制及非限制级抗菌药物的AUD值有所上升,且非限制级抗菌药物的AUD值上升较为明显,但非基本药物的AUD值远高于基本药物。结论:该院存在AUD值偏高、用药集中、广谱抗菌药物的使用率高等问题,应加强监管并优化抗菌药物使用品种,力争将AUD降至40 DDDs/(100人·d)以下。
[Abstract]:Objective: to provide reference for the long-term management of antimicrobial agents. Methods: the data of antimicrobial use in the hospital from 2012 to 2013 were collected retrospectively. The statistical data were collected by Excel 2003, and the intensity of antimicrobial agents was calculated and compared with that of Excel 2003. Results: the AUD value of the hospital was stable in 2012 and the AUD value in 2013 was 40.46% and 42.56 DDDs/(100, respectively, which was close to the target, but still had a certain distance. The AUD value of half of the departments in 2013 was higher than that in 2012, including respiratory department, intensive medicine department and dermatology department. The AUD value of rehabilitation department and burn orthopedics department increased greatly. The kinds of antibiotics in the top 5 places remained unchanged: penicillin enzyme inhibitors, third generation cephalosporins, quinolones, etc. The second generation cephalosporins and penicillin. AUD were the top 20 drugs. The AUD value of special use class antimicrobial agents decreased significantly in 2013, while the AUD value of restricted and unrestricted class antimicrobial drugs increased, the second generation cephalosporins and penicillin. The AUD value of non-restricted class antibiotics increased significantly, but the AUD value of non-essential drugs was much higher than that of essential drugs. Conclusion: there are some problems in the hospital, such as high AUD value, concentrated drug use and high utilization rate of broad-spectrum antimicrobial agents. It is necessary to strengthen supervision and optimize the variety of antimicrobial agents used in order to reduce AUD to less than 40 DDDs/(100 per person (dd).
【作者单位】：嘉兴市第一医院;
【分类号】：R95

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