某院门诊奥美拉唑超说明书用药情况调查分析

发布时间：2018-05-04 17:19

本文选题：门诊 + 奥美拉唑　；参考：《中国药房》2017年35期

【摘要】：目的:调查门诊奥美拉唑超说明书用药情况,为临床合理用药提供参考。方法:采用回顾性调查的方法,并用随机数字表法抽取某院门诊2014年6月-2017年5月使用奥美拉唑的处方1 838张,根据最新版药品说明书,判断是否超说明书用药;通过查阅国内外指南、文献和Micromedex数据库等对超说明书用药进行分析。结果:1 838张处方中,超说明书用药处方有1 750张(95.21%),涉及3种类型、13项超说明书用药内容。超说明书用药类型主要为超适应证用药,共1 747张(96.47%)。消化内科和非消化内科超说明书用药发生率、不同级别医师超说明书用药发生率比较,差异均无统计学意义(P0.05)。13项超说明书用药内容中,7项有国内外指南、专家共识/建议或文献报道等不同级别的循证医学证据支持,但其中仅有1项被Micromedex的Thomson分级系统收录,其余6项均无任何循证医学证据。结论:该院门诊奥美拉唑超说明书用药现象普遍,部分超说明书用药有证据支持,但各证据质量存在差异。临床应规范说明书应用以避免法律风险,确保患者安全用药。
[Abstract]:Objective: to investigate the drug usage of Omeprazole superscript in outpatient clinic and to provide reference for rational use of Omeprazole in clinic. Methods: 1 838 Omeprazole prescriptions were collected from outpatients of a hospital from June 2014 to May 2017 by retrospective investigation and random digital table method. According to the latest version of drug instructions, whether the prescriptions were over-prescribed or not was judged. By consulting the domestic and foreign guidelines, literature and Micromedex database to analyze the hypermanual drug use. Results among the 1 838 prescriptions, there were 1 750 prescriptions in the overstatement, involving 13 items in 3 kinds of prescriptions. The main types of drug use in superscript were super indications, a total of 1 747 pieces of drug. There were no significant differences in the incidence of over-instruction drug use between internal medicine department and non-digestive internal medicine department, and there were no significant differences in the incidence rate of over-instruction drug use among doctors of different grades. There were no statistical significance in 7 of the 13 items of hyperinstruction drug use content, which had domestic and foreign guidelines. The expert consensus / recommendation or literature reports supported the evidence of evidence-based medicine at different levels, but only one of them was included in Micromedex's Thomson classification system, and the other 6 items were not supported by any evidence of evidence-based medicine. Conclusion: Omeprazole superscript drug use is common in outpatient department of our hospital, some of them are supported by evidence, but the quality of evidence is different. Clinical specifications should be standardized to avoid legal risks and ensure safe use of drugs for patients.
【作者单位】：广州中医药大学附属广东中西医结合医院;广东省中西医结合医院药学部;广东省中西医结合医院消化内科;
【基金】：广东省医院药学研究基金项目(No.2016A22)
【分类号】：R975

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