临床药师参与口服靶向药物不良反应的管理模式及效果评价

发布时间：2018-05-11 21:33

本文选题：临床药师 + 靶向药物　；参考：《中国药学杂志》2015年19期

【摘要】：目的通过构建不良反应管理团队,临床药师直接参与口服靶向药物不良反应的管理,优化管理患者长期口服靶向药物安全性。方法建立不良反应事件管理团队,临床药师对患者实施全程监护。收集我院54例口服吉非替尼的出院肺癌患者,对其在院期间实施用药教育,出院后定期电话随访,同时加强用药教育,指导不良反应的处理措施。调查药学监护后患者对靶向药物的认知度情况。结果通过构建医、药、护医疗团队对口服靶向药物患者集中管理,临床药师直接参与患者长期口服靶向药物药学监护,定期随访为患者提供药学服务,可降低靶向药物的不良反应严重程度,提高患者对靶向药物的认识度及不良反应的接受度。结论建立药师定期随访加强用药教育可预先管理长期口服靶向药物的不良反应,同时实现患者的自我管理,优化患者长期口服靶向药物的治疗结果,提高患者用药依从性和生活质量。
[Abstract]:Objective through the construction of adverse drug management team, clinical pharmacists are directly involved in the management of oral targeted drug adverse reactions and optimize the safety of long-term oral drug targeting drugs for patients. Methods to establish adverse event management team and clinical pharmacists to carry out full monitoring of the patients. 54 cases of lung cancer patients in our hospital were collected, and the patients who were discharged from the hospital were collected. The medication education was carried out during the hospital, followed up by telephone regularly after discharge. At the same time, the drug education was strengthened and the treatment measures of adverse reactions were directed. The awareness of the target drug after the pharmaceutical care was investigated. The result was that the medical, drug and medical team had centralized management of the patients with oral target drugs, and the clinical pharmacists were directly involved in the patient's length. Oral targeting drug pharmaceutical care, regular follow-up for patients with pharmaceutical care, can reduce the severity of adverse drug reactions to targeted drugs, improve the awareness of targeted drugs and acceptance of adverse reactions. Conclusion a regular follow-up of pharmacists to strengthen medication education can premanage the adverse reactions of long-term oral targeted drugs. To achieve self-management of patients, optimize the long-term treatment results of oral targeted drugs, improve patient compliance and quality of life.

【作者单位】：福建医科大学省立临床医学院;福建省立医院药学部;
【分类号】：R95

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