阿立哌唑致不良反应67例文献分析

发布时间：2018-05-19 01:31

本文选题：阿立哌唑 + 不良反应　；参考：《中国药房》2015年03期

【摘要】：目的:探讨阿立哌唑致不良反应(ADR)的一般规律和特点,为临床合理用药提供参考。方法:检索2002-2013年我国医药期刊报道的阿立哌唑致ADR病例,并就收集到的67例ADR相关信息进行分类、统计和分析。结果:阿立哌唑致ADR与性别无关,多发生于20~39岁;用药6个月内ADR发生率较高;以神经系统及心血管系统损害较为多见。66例患者均恢复正常,1例患者因Ⅲ度房室传导阻滞未恢复正常。结论:尽管阿立哌唑安全性和耐受性均较好,但临床仍需高度重视用药监测,以减少ADR的发生,确保用药安全。
[Abstract]:Objective: to study the general rule and characteristics of ADR induced by aripiprazole and to provide reference for rational drug use. Methods: a total of 67 cases of ADR caused by aripiprazole from 2002 to 2013 were searched for classification, statistics and analysis. Results: the incidence of ADR caused by aripiprazole was not related to sex, most occurred in 20 to 39 years old, and the incidence of ADR was higher within 6 months after treatment. Among them, the damage of nervous system and cardiovascular system was more common in 66 patients. One patient did not return to normal because of the third degree atrioventricular block. Conclusion: although aripiprazole is safe and tolerant, it is necessary to attach great importance to drug monitoring in order to reduce the incidence of ADR and ensure the safety of drug use.
【作者单位】：河池市复退军人医院;河池市第四人民医院药剂科;
【分类号】：R971

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