Ⅰ类切口围手术期预防性使用抗菌药物干预分析

发布时间：2018-05-23 07:40

  本文选题：Ⅰ类手术切口 + 围手术期　； 参考：《中华医院感染学杂志》2015年13期

【摘要】：目的研究经全国抗菌药物临床应用专项整治以及等级医院评审的药学干预后乳腺、甲状腺手术、腹股沟疝修补术3种Ⅰ类切口手术围术期预防性使用抗菌药物的合理性。方法随机选取2010年7-12月和2013年7-12月3种手术Ⅰ类切口病历各100份,对围手术期预防性抗菌药物的使用率、选用药物品种、给药时机、用药持续时间及伤口愈合等进行对比。结果 3种Ⅰ类切口手术抗菌药物使用率由干预前的99.3%降至干预后12.0%,乳腺手术、甲状腺手术、疝气手术的抗菌药物使用率分别由干预前的98.0%、100.0%、100.0%,降至干预后的16.0%、11.0%、9.0%;合理应用率高达91.0%;整改后的300例患者无切口感染,并且切口甲级愈合占98.3%;Ⅰ类切口手术预防用抗菌药物的用药品种,由2010年的三代头孢菌素使用率62.3%改进为2013年的一代头孢菌素的使用率88.9%,并且杜绝了无依据的更换药品。结论药学干预与行政干预显著降低了Ⅰ类切口手术抗菌药物预防性使用率,提高了抗菌药物使用的合理率。
[Abstract]:Objective to study the rationality of prophylactic use of antimicrobial agents in breast, thyroid surgery and inguinal herniorrhaphy after clinical treatment of antimicrobial agents in China and the pharmacological intervention evaluated by grade hospitals during perioperative period. Methods A total of 100 medical records of three types of surgical incision were randomly selected from July to December 2010 and from July to December 2013 respectively. The utilization rate of prophylactic antimicrobial agents during perioperative period, the choice of drugs, the timing of administration, the duration of medication and wound healing were compared. Results the utilization rate of antibiotics decreased from 99.3% before intervention to 12.0% after intervention. The utilization rate of antibiotics in hernia surgery was reduced from 98.0 / 100.0g / 100.0g before intervention to 16.0 / 11.0/ 9.0after the intervention, and the reasonable application rate was as high as 91.0 / 91.The 300 patients after the correction had no incisional infection. The rate of utilization of cephalosporins in the third generation of cephalosporins in 2010 was improved from 62.3% to 88.9% in 2013, and the unwarranted replacement of drugs was eliminated. Conclusion Pharmacological intervention and administrative intervention can significantly reduce the prophylactic utilization rate of antimicrobial agents and increase the rational rate of use of antibiotics in class 鈪，

本文编号：1923854