我院常用口服抗高血压药说明书中老年人用药信息的调查分析

发布时间：2018-05-27 05:40

本文选题：抗高血压药 + 药品说明书　；参考：《中国药房》2015年29期

【摘要】：目的:保障老年人用药安全。方法:收集我院38种常用口服抗高血压药说明书,并对其国内外生产厂家的说明书中老年人用药的标注情况等进行调查分析。结果:在所调查的药品说明书中,给出了具体的老年人用药剂量的21份;占55.26%,有"老年人用药"明确标注的16份,占42.11%;有老年人的药动学研究的15份,占39.47%。除血管紧张素受体拮抗药类抗高血压药外,其他几类抗高血压药物相关标注低。标注"低剂量开始使用"占21.05%。标注"无需调整剂量"、"慎重用药"、"无年龄差异"的分别占15.79%、15.79%、13.16%,其余标注率低。国产药品说明书中老年人用药内容的相关标注低于进口药品说明书。结论:常用口服抗高血压药说明书存在用法用量、用药注意事项、药动学、表述不详尽等问题,药品监管部门和药品生产者应共同努力完善说明书的内容,保障老年人用药安全。
[Abstract]:Objective: to ensure the safety of drug use in the elderly. Methods: 38 kinds of oral antihypertensive drugs were collected and analyzed. Results: of the drug instructions investigated, 21 were given specific dosage for the elderly, accounting for 55.26, 16 (42.11) and 15 (39.47), respectively, which were clearly labeled as "drug for the elderly" and 15 (39.47) for the pharmacokinetics of the elderly. With the exception of angiotensin receptor antagonists, several other antihypertensive drugs have low labeling. Marked "low dose start use" accounted for 21.05%. "No adjustment dose", "careful medication", "no difference in age" accounted for 15.79 ~ 15.79% and 13.16% respectively, and the other labeling rates were low. The related labeling of the drug content of the elderly in the domestic drug instruction is lower than that of the imported drug instruction. Conclusion: the commonly used oral antihypertensive drug instructions have some problems, such as usage amount, medication matters needing attention, pharmacokinetics, non-exhaustive description, etc. The drug supervision department and drug producer should make joint efforts to perfect the contents of the instructions. To ensure the safety of drug use for the elderly.
【作者单位】：天津市职业病防治院/工人医院药剂科;
【分类号】：R95

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