不同钙剂对男性多次双份机采献血者影响的研究

发布时间：2018-05-29 18:49

本文选题：葡萄糖酸钙 + 双份机采　；参考：《中国输血杂志》2015年05期

【摘要】：目的研究口服碳酸钙和葡萄糖酸钙对男性多次机采献血者双份机采中血清钙、磷和甲状旁腺素(PTH)的影响。方法随机抽取男性多次机采献血者77例,随机的分为3组:未补钙组,葡萄糖酸钙组(采前20 min口服葡萄糖酸钙4支,元素钙360 mg),碳酸钙组(采前20 min口服碳酸钙2片,元素钙1 200 mg),检测献血者机采前-20 min)、机采开始(0 min)、机采中(40 min)、后(80 min)血清钙、磷和PTH含量,观察献血者的柠檬酸盐抗凝剂相关反应。结果双份机采后,3个组的钙分别为(2.13±0.06),(2.23±0.07),(2.23±0.07)mmol/L;3个组双份机采后的PTH分别为(153±57),(121±35),(104±40)pg/L;机采中和机采后3组的钙、PTH比较,均为P0.01;采集后碳酸钙组与葡萄糖酸钙组比较,血清钙和PTH比较,葡萄糖酸钙、碳酸钙组与未补钙组比较,轻度抗凝剂反应的发生率均为P0.05。结论口服碳酸钙和葡萄糖酸钙能有效稳定机采中血清钙,PTH的波动,献机采前20 min口服碳酸钙是值得推荐的。
[Abstract]:Objective to study the effects of calcium carbonate and calcium gluconate on serum calcium, phosphorus and parathyroid hormone (PTH) in male multiple machine mining donors. Methods 77 male blood donors were randomly selected and randomly divided into 3 groups: non calcium supplementation group, calcium gluconate group (20 min oral calcium gluconate, 360 mg), and carbon Calcium acid group (2 tablets of calcium carbonate before mining 20 min, element calcium 1200 mg), -20 min before extraction of blood donors, machine mining (0 min), mechanical mining (40 min), and post (80 min) serum calcium, phosphorus and PTH content, observe the reaction of citrate anticoagulants in blood donors. The results were (2.13 + 0.06), (2.23 + 0.07), (2.23 + 40), respectively (2.23 + 0). .07) mmol/L; the PTH of the 3 groups after extraction was (153 + 57), (121 + 35) and (104 + 40) pg/L, and P0.01 was all compared with the calcium gluconate group, calcium carbonate group and calcium gluconate group, calcium gluconate, calcium carbonate group and non calcium supplementation group, the incidence of mild anticoagulant reaction was P0.. 5 Conclusion oral calcium carbonate and calcium gluconate can effectively stabilize the fluctuation of serum calcium and PTH, and it is recommendable to offer oral calcium carbonate 20 min before harvest.
【作者单位】：深圳市血液中心;
【基金】：深圳市卫生计生系统科研项目(201402092)
【分类号】：R969

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