血管介入术抗菌药物预防应用临床研究

发布时间：2018-06-21 23:46

本文选题：抗菌药物 + 血管介入术　；参考：《中华医院感染学杂志》2015年02期

【摘要】：目的探讨抗菌药物的预防应用对血管介入术后感染的影响,为临床合理应用抗菌药物提供参考。方法选取医院2010年1月-2013年6月386例进行血管介入术的住院患者作为研究对象,将其随机均等的分为观察组和对照组两组,各193例;观察组在手术前1h给予适量的抗菌药物预防,对照组不给于抗菌药物,直接进行手术;对比两组患者的一般情况、手术后的相关症状和感染的发生率。结果两组基本资料比较差异无统计学意义;对比观察组和对照组的相关症状发热、C-反应蛋白及中性粒细胞升高结果显示,差异无统计学意义;观察组和对照组接受血管介入术后患者的感染情况对比,观察组发生感染的患者有5例,感染率为2.59%,对照组感染的患者有6例,感染率为3.11%,两组比较差异无统计学意义。结论抗菌药物的预防应用对血管介入术后感染率方面的影响无相关性,因此在临床上没有必要预防性应用,在一定程度上可以降低抗菌药物的耐药性。
[Abstract]:Objective to explore the effect of prophylactic use of antibiotics on infection after vascular intervention, and to provide reference for rational use of antibiotics in clinic. Methods 386 inpatients undergoing vascular intervention from January 2010 to June 2013 were randomly divided into two groups: observation group and control group with 193 cases in each group. The observation group was treated with appropriate amount of antimicrobial agents at 1 hour before operation, while the control group was not given antibiotics, and the patients in the two groups were treated directly. The general situation of the two groups, the related symptoms and the incidence of infection after operation were compared. Results there was no significant difference in the basic data between the two groups, but there was no significant difference between the observation group and the control group in the elevation of C-reactive protein and neutrophil. There were 5 cases of infection in the observation group and 5 cases in the control group, the infection rate was 2.59. In the control group, there were 6 cases of infection, and the infection rate was 3.11. There was no significant difference between the two groups. Conclusion the prophylactic use of antimicrobial agents has no correlation with the infection rate after vascular interventional surgery, so it is not necessary to use prophylactic drugs in clinic, and to some extent can reduce the drug resistance of antimicrobial agents.
【作者单位】：贵阳医学院附属医院放射科;
【基金】：贵州省科技计划基金资助项目(黔科合LG字2012-058)
【分类号】：R978.1

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