某省级精神卫生中心2002—2011年抗精神病药物用药频度分析

发布时间：2018-08-09 15:01

【摘要】：目的了解某省级精神卫生中心2002—2011年抗精神病药物的使用情况,为精神科药物使用政策的制定提供客观依据。方法收集河北省精神卫生中心2002、2006、2011年度的药品出库记录,以限定日剂量(DDD)为指标,运用药物经济学用药频度(DDDs)分析方法,并结合药品总销售金额,对精神科药物使用情况进行分析。结果该机构抗精神病药物选择范围逐渐增加,2011年较2002年抗精神病药物品种增加了33.33%(4/12),非典型抗精神病药物所占品种数由2002年的25.00%(3/12)上升至2011年的56.25%(9/16)。抗精神病药物的销售金额及DDDs呈现上升趋势,复合增长率分别达26.71%和4.51%。非典型抗精神病药物的销售金额(30.39%)和DDDs(15.71%)稳步增长,其构成比也相应增加,而典型抗精神病药物销售金额(-12.68%)及DDDs(-13.95%)呈负增长态势。2011年DDDs排名前5位的均为非典型抗精神病药物,分别是喹硫平、奥氮平、利培酮、氯氮平、阿立哌唑。非典型抗精神病药物价格日趋合理,除氯氮平外其余药品总销售金额排序与DDDs排序的比值(B/A)整体呈上升趋势,至2011年利培酮和喹硫平B/A≥1。结论该机构使用的主要抗精神病药物已经由传统的典型抗精神病药物转向以喹硫平、奥氮平、利培酮为主的非典型抗精神病药物。根据药物使用趋势,建议卫生行政部门适时调整医保药物政策。
[Abstract]:Objective to understand the use of anti psychotic drugs in a provincial mental health center from 2002 to 2011, and to provide an objective basis for the formulation of the policy for the use of psychotropic drugs. Methods the record of drug delivery in Hebei mental health center in 200220062011 was collected to limit the daily dose (DDD) as an indicator and to use the pharmacoeconomic frequency of drug use (DDDs). The analysis method, combined with the total amount of drug sales, analyzed the use of psychotropic drugs. Results the selection range of anti psychotic drugs increased gradually. In 2011, anti psychotic drugs increased by 33.33% (4/12) compared with 2002, and the number of atypical antipsychotic drugs increased from 25% (3/12) in 2002 to 56.25 in 2011. % (9/16). The sales amount of antipsychotic drugs and DDDs showed an upward trend, with a compound growth rate of 26.71% and 4.51%. atypical antipsychotics, the sales amount (30.39%) and DDDs (15.71%) increased steadily, and their constituent ratio increased correspondingly, while the sales amount of the typical antipsychotics (-12.68%) and DDDs (-13.95%) were negative growth.2011 DDDs in the top 5 were atypical antipsychotic drugs. The price of quetiapine, olanzapine, risperidone, clozapine, and aripiprazole. The price of atypical antipsychotic drugs is becoming more and more reasonable. The ratio of the total sales amount of other drugs except for clozapine (B/A) is on the rise, and the rate of risperidone and quetiapine in 2011 is higher than that of the DDDs. 1. conclusion the main antipsychotic drugs used by the agency have shifted from traditional antipsychotic drugs to atypical antipsychotic drugs based on quetiapine, olanzapine and risperidone. According to the trend of drug use, the health administration department is advised to adjust the medical policy in a timely manner.
【作者单位】：河北省精神卫生中心(河北省第六人民医院);
【分类号】：R971

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