某三甲医院抗菌药物临床应用专项整治活动效果分析

发布时间：2018-08-20 15:00

【摘要】：目的了解某三甲医院抗菌药物临床应用专项整治活动前后抗菌药物使用情况。方法抽取四川省某三甲医院2011年1月—2013年12月的抗菌药物使用数据,对抗菌药物品种、门急诊抗菌药物处方比例、住院患者抗菌药物使用费用占总费用比、抗菌药物使用率和使用强度、特殊使用级抗菌药物使用率和使用强度、接受限制和特殊使用级抗菌药物患者微生物送检率等数据进行回顾性分析。结果抗菌药物临床应用整治活动前,医院抗菌药物品种有88种,整治后一直保持在50种。整治活动后门急诊抗菌药物处方比和住院抗菌药物费用占总费用比均小于整治活动前(均P0.05)。整治前后抗菌药物使用率、特殊使用级抗菌药物使用率比较,差异均有统计学意义(均P0.05)。整治后接受限制和特殊使用级抗菌药物患者的微生物送检率也显著高于整治前(均P0.05)。整治后医院Ⅰ类切口手术围手术期抗菌药物预防用药率低于整治前,而术前30 min~2 h用药比例高于整治前(均P0.05)。结论 3年专项整治使医院抗菌药物的使用更趋合理,但仍需进一步加强管理,促进抗菌药物合理应用工作持续改进。
[Abstract]:Objective to investigate the use of antimicrobial drugs before and after special treatment activities in a third class hospital. Methods the data of antimicrobial use from January 2011 to December 2013 in a third Class A Hospital in Sichuan Province were collected. The antimicrobial drug varieties, the proportion of antimicrobial prescriptions in outpatient and emergency department, and the cost of antimicrobial use in inpatients accounted for the total cost. The utilization rate and intensity of antimicrobial agents, the utilization rate and intensity of antimicrobial agents of special use grade, and the microbiological examination rate of patients with restricted and special use classes of antibiotics were analyzed retrospectively. Results there were 88 kinds of antimicrobial agents in hospital before the treatment of clinical application of antimicrobial agents and 50 kinds of antimicrobial agents were maintained after treatment. The ratio of antimicrobial prescription and cost of antibiotics in outpatient and emergency department was lower than that before treatment (P0.05). Before and after treatment, the utilization rate of antimicrobial agents and the utilization rate of special use class antibiotics were significantly different (P0.05). The microbiological examination rate of patients receiving restricted and special antibiotics after treatment was significantly higher than that before treatment (P0.05). The prophylactic use rate of antimicrobial drugs in the perioperative period was lower than that before treatment, and the proportion of antibiotics used 30 min~2 before operation was higher than that before treatment (P0.05). Conclusion the use of antimicrobial agents in hospitals is more reasonable after three years of special treatment, but it is still necessary to strengthen the management and promote the continuous improvement of rational use of antibiotics.
【作者单位】：四川大学华西医院;
【分类号】：R95

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