临床用药差错归因分析及药师的干预效果评价

发布时间：2018-09-08 11:48

【摘要】：目的:对用药差错进行归因分析,并评价用药差错可能造成的危害,以减少因用药差错而导致的药品不良事件的发生。方法:将我院2010年3月1日-5月30日的患者病历设为基准期,2011年同期患者病历设为干预期,分析引起用药差错的各种因素,并对用药差错的潜在危害和药师干预效果进行评估。结果:共收到168份用药差错报告,其中基准期115份、干预期53份,用药差错率分别为2.26%(115/5084)和0.94%(53/5637),二者比较差异有统计学意义(P0.05);潜在危害程度严重者16份(0.32%)和5份(0.09%),中度者46份(0.90%)和25份(0.44%),轻度者53份(1.04%)和23份(0.41%),差异均有统计学意义(P0.05);用药差错主要表现在药品使用、频次、时间、剂量等方面;干预期53份报告中46份被临床采纳,采纳率达86.8%。结论:用药差错会给患者的药物治疗带来较大风险,临床药师干预可有效降低用药差错所导致的风险。
[Abstract]:Objective: to analyze the attribution of drug errors and evaluate the possible harm caused by drug errors in order to reduce the occurrence of adverse drug events caused by drug errors. Methods: the patient's medical records of our hospital from March 1 to May 30, 2010 were set up as the reference period, and the patient's medical records in the same period of 2011 were set as dry expectation. The factors causing drug errors were analyzed, and the potential harm of drug errors and the effect of pharmacist intervention were evaluated. Results: a total of 168 drug error reports were received, including 115 in the base period and 53 in dry expectations. The drug error rates were 2.26% (115 / 5084) and 0.94% (53 / 5637) respectively, the difference was statistically significant (P0.05), there were significant differences in 16 (0.32%) and 5 (0.09%) cases with severe potential hazard, 46 (0.90%) and 25 (0.44%) in moderate, 53 (1.04%) and 23 (0.41%) in mild (P 0.05). Drug use errors are mainly manifested in drug use. Frequency, time, dose, etc. 46 of the 53 reports were clinically accepted, and the adoption rate was 86.8%. Conclusion: medication errors may bring greater risk to patients' drug treatment, and intervention by clinical pharmacists can effectively reduce the risk caused by drug errors.
【作者单位】：天津市河西医院;
【分类号】：R95

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