广西9家“三甲”医院头孢菌素类抗菌药物对胆囊结石切除术患者住院费用和住院天数的影响分析

发布时间：2018-09-12 14:38

【摘要】：目的:考察头孢菌素类抗菌药物对胆囊结石切除术患者住院费用和住院天数的影响,为其临床应用提供参考。方法:收集广西9家"三甲"医院2013-2014年入院,经手术治疗后已出院的胆囊结石患者资料,共1 866例。采用SPSS 22.0软件对胆囊结石切除术患者的住院费用和住院天数的影响因素进行分析。结果:多因素分析结果显示,抗菌药物、医院、年龄、手术类型、出院诊断病种数均为明显影响住院费用和住院天数的因素(均为P0.01)。按照住院费用,抗菌药物被分成1~4档,第1档仅含头孢呋辛(9 454元),第2档含非头孢菌素类(16 199元)和五水头孢唑林(17 241元),第3档含头孢他啶(20 716元)、其他头孢菌素类(21 046元)和头孢噻肟舒巴坦(22 724元),第4档含头孢噻肟舒巴坦(22 724元)、头孢哌酮舒巴坦(23 688元)、头孢西丁(24 685元)和头孢地嗪(24 698元);按照住院天数,抗菌药物同样被分成1~4档,第1档仅含非头孢菌素类(7.61 d),第2档含头孢呋辛(8.94d)和五水头孢唑林(9.78 d),第3档含头孢西丁(13.39 d)、头孢地嗪(13.44 d)、其他头孢菌素类(14.32 d)和头孢他啶(14.60 d),第4档含头孢哌酮舒巴坦(16.03 d)和头孢噻肟舒巴坦(16.91 d)。档数越大其对应的住院费用越高或住院天数越长,不同档次之间差异有统计学意义(P0.05),同档次内则差异无统计学意义(P0.05)。结论:头孢菌素类抗菌药物品种的选择可以明显影响胆囊结石切除术患者的住院费用和住院天数,临床可根据本地医疗资源和患者要求综合考虑。
[Abstract]:Objective: To investigate the effect of cephalosporins on hospitalization expenses and days of hospitalization in patients undergoing cholecystolithiasis resection, and to provide reference for clinical application.Methods: Data of 1 866 patients with cholecystolithiasis admitted to 9 hospitals in Guangxi from 2013 to 2014 were collected. Results: Multivariate analysis showed that antibiotics, hospital, age, type of operation, and number of discharged diagnostic diseases were all significant factors affecting hospitalization expenses and length of stay (all P 0.01). According to hospitalization expenses, antibiotics were divided into 1-4 groups, and the first group contained only antibiotics. Cefuroxime ($9,454), non-cephalosporins ($16,199) and cefazolin pentahydrate ($17,241), ceftazidime ($20,716), other cephalosporins ($21,046) and cefotaxime sulbactam ($22,724), cefoperazone sulbactam ($23,688), cefoxitin ($24,685) and cefotaxime sulbactam ($22,724), cefoperazone sulbactam ($23,688), cefoxitin ($24,685) and cefoxitin ( Cefodizime (24,698 yuan) was also classified into 1 to 4 groups according to length of stay, including only non-cephalosporins (7.61 days) in the first group, cefuroxime (8.94 days) and cefazolin pentahydrate (9.78 days) in the second group, cefoxitin (13.39 days), cefodizime (13.44 days), other cephalosporins (14.32 days) and ceftazidime (14.60 days) in the third group, and ceftazidime (14.60 days) in the fourth group. Foperazone sulbactam (16.03 d) and cefotaxime sulbactam (16.91 d). The higher the grade, the higher the hospitalization expenses or the longer the hospitalization days, the difference between different grades was statistically significant (P 0.05), but there was no significant difference within the same grade (P 0.05). Conclusion: The choice of cephalosporins antibiotics can significantly affect gallbladder node. The hospitalization cost and length of stay of stone resection patients can be considered according to local medical resources and patient requirements.
【作者单位】：广东省中医院心理睡眠专科;广西壮族自治区人民医院肝胆外科;广西壮族自治区人民医院药学部;
【基金】：广西医疗卫生适宜技术研究与开发课题(No.S201420-02)
【分类号】：R657.42;R95

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