中国医院感染管理部门在抗菌药物合理应用与管理工作中的发展状况

发布时间：2018-10-16 20:35

【摘要】：目的了解我国医院感染管理部门在抗菌药物临床合理应用与管理中发展状况。方法抽取全国12个省、直辖市、自治区及军队医院166所医院作为调查对象,比较不同年份医院感染管理部门在各项抗菌药物合理应用与管理工作中的参与情况。结果166所医院中,2005年参与抗菌药物合理应用管理组织建设的医院68所(40.96%),2010年增至119所(71.69%),2015年为160所(96.39%),经趋势性χ2检验,差异有统计学意义(χ2=121.143,P0.001)。医院感染管理科参与抗菌药物管理的比率也呈上升趋势(χ2=22.172,P0.001),由2005年的10.24%(17所),上升至2010年的22.29%(37所)、2015年的31.33%(52所)。医院抗菌药物品种及药品分级目录的制订、抗菌药物使用权限的规定,医院感染管理科参与抗菌药物管理小组、细菌耐药性监测、清洁切口预防用药管理、抗菌药物临床应用检查、临床会诊工作、处方点评工作的比率:2005年为10.87%~30.72%,2010年为25.90%~65.06%,2015年为36.14%~95.18%,各项工作3年均呈增长趋势,差异均有统计学意义(均P0.01)。医院抗菌药物使用强度(AUD,DDD/100人天)由2005年的69.16下降至2015年的41.40,抗菌药物使用率由2005年的46.98%,下降至2015年的36.90%,治疗性使用抗菌药物患者病原送检率由2005年的20.58%提高至2015年的49.39%。结论中国医院感染管理部门在抗菌药物合理应用与管理中发挥了重要作用。
[Abstract]:Objective to understand the development of rational use and management of antimicrobial drugs in hospital infection management department in China. Methods 166 hospitals in 12 provinces, municipalities, autonomous regions and military hospitals were selected to compare the participation of nosocomial infection management departments in the rational application and management of antimicrobial agents in different years. Results among 166 hospitals, 68 hospitals (40.96%) participated in the management of rational use of antimicrobial agents in 2005, which increased to 119 (71.69%) in 2010 and 160 (96.39%) in 2015. The difference was statistically significant (蠂 ~ 2 + 121.143) by 蠂 ~ 2 test. The rate of participation of hospital infection management department in antimicrobial drug management also showed an increasing trend (蠂 2 22. 172 P 0. 001), from 10. 24% (17) in 2005 to 22. 29% (37) in 2010, and 31. 33% (52) in 2015. The formulation of categories and classification of antimicrobial drugs in hospitals, the provisions of the authority for the use of antibiotics, the participation of hospital infection management departments in the management of antimicrobial agents, the monitoring of bacterial resistance, and the administration of prophylactic drug use through clean incisions, The rates of clinical application examination, clinical consultation and prescription evaluation were 10.87 in 2005, 25.90 in 2010, 65.06 in 2010, 36.14 in 2015 and 95.18 in 2015. All the work showed an increasing trend in three years (all P 0.01). The intensity of antimicrobial use (AUD,DDD/100 man days) in hospitals decreased from 69.16 in 2005 to 41.40 in 2015. The utilization rate of antimicrobial agents decreased from 46.98 in 2005 to 36.90 in 2015. The pathogenic rate of patients with therapeutic use of antimicrobial drugs increased from 20.58 percent in 2005 to 49.39 in 2015. Conclusion the hospital infection management department in China plays an important role in the rational use and management of antimicrobial agents.
【作者单位】：中南大学湘雅医院;北京大学第一医院;广东省人民医院;新疆医科大学第一附属医院;内蒙古自治区人民医院;江西省儿童医院;安徽医科大学第一附属医院;郑州大学第一附属医院;北京大学人民医院;河北医科大学第四医院;山东省立医院;贵州省人民医院;山西医学科学院山西大医院;江苏省人民医院;敦煌市医院;福建医科大学附属肿瘤医院;
【分类号】：R197.323.4

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