医院专项整治前后抗菌药物使用强度与合理用药分析

发布时间：2018-10-22 08:54

【摘要】：目的分析医院2011年至2014年住院患者抗菌药物使用强度及抗菌药物用药频度(DDDs)与近4年医院病原菌分布关系,为临床合理使用抗菌药物和其他类别药物提供参考。方法回顾性分析医院2011年至2014年的抗菌药物使用情况,以限定日剂量(DDD)为单位,以每100人每天消耗的抗菌药物DDDs计算抗菌药物使用强度,对医院近4年细菌病原菌分布进行统计分析。结果医院2011年至2014年全院住院患者抗菌药物平均用药强度分别为64.26,41.73,39.00,33.93,抗菌药物使用强度呈下降趋势。青霉素类+酶抑制剂、第1,2代头孢、其他β-内酰胺类与阿莫西林舒巴坦、头孢哌酮舒巴坦钠、头孢硫眯、头孢他啶位于各类别及各品种抗菌药物用药强度的前3位。科室中,呼吸科、重症监护室(ICU)、儿科菌药物使用强度排名靠前,院内细菌中分离量较大的分别是大肠埃希菌、肺炎克雷伯菌和金黄色葡萄球菌,该院排名前3的抗菌药物品种选用基本合理。结论医院专项整治活动的开展对抗菌药物的使用起到了较好的效果,各科室抗菌药物的合理使用有了进一步的加强,继续以抗菌药物专项整治活动为契机,全面促进医院的合理用药水平。
[Abstract]:Objective to analyze the relationship between the intensity of antimicrobial use and the frequency of antimicrobial use (DDDs) and the distribution of pathogenic bacteria in hospital in recent four years from 2011 to 2014, so as to provide reference for rational use of antimicrobial agents and other kinds of drugs in clinic. Methods the use of antimicrobial agents in hospitals from 2011 to 2014 was retrospectively analyzed. The intensity of antimicrobial use was calculated by the daily consumption of antimicrobial agents (DDDs) per 100 people in a defined daily dose of (DDD). The distribution of bacterial pathogens in hospital in recent 4 years was analyzed statistically. Results from 2011 to 2014, the average intensity of antimicrobial agents was 64.26 ~ 41.73 ~ 39.00 ~ 33.93, respectively. The intensity of antimicrobial use showed a decreasing trend. Penicillin inhibitors, second generation cephalosporins, other 尾-lactams and amoxicillin sulbactam, cefoperazone sulbactam sodium, cefthiumine, ceftazidime were in the top 3 of the antimicrobial agents of each class and variety. In the department, respiratory department, intensive care unit (ICU), (ICU), paediatric bacteria drug use intensity ranked first, the large amount of bacteria isolated in the hospital were Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus, respectively. The hospital ranked the top 3 antimicrobial variety selection is basically reasonable. Conclusion the development of special treatment activities in hospitals has played a better role in the use of antimicrobial agents, and the rational use of antimicrobial drugs in various departments has been further strengthened, taking the special treatment activities of antimicrobial drugs as an opportunity. To promote the level of rational use of drugs in hospitals.
【作者单位】：云南省大理市第一人民医院;
【分类号】：R95

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