肝胆外科住院患者抗菌药物应用分析

发布时间：2018-10-22 16:52

【摘要】：目的了解肝胆外科住院患者的抗菌药物应用及其合理性,为临床合理使用抗菌药物提供参考依据。方法回顾性分析医院2010年1月-2013年10月收治的260例肝胆外科住院患者临床资料,调查其抗菌药物的应用并分析其用药合理性。结果 260例患者中有242例使用了抗菌药物,抗菌药物的使用率达93.08%;242例用药患者中所涉及的抗菌药物约8大类、22个品种;使用最多的为头孢菌素类、青霉素类、喹诺酮类以及硝咪唑类抗菌药物;普遍存在联合用药的现象,联用2种抗菌药物者78例占32.23%,联合3种抗菌药物者67例占27.69%,联用3种抗菌药物者53例占21.90%,最常用的三联抗菌药物为甲硝唑+头孢类+喹诺酮类或氨基糖苷类;260例患者中仅有43例患者进行了病原菌检测,送检率为16.54%。结论肝胆外科住院患者抗菌药物的使用基本遵循有效、安全的原则,但仍然有少数患者存在用药不合理现象,值得警惕和改善。
[Abstract]:Objective to investigate the application and rationality of antibiotics in patients with hepatobiliary surgery, and to provide reference for rational use of antimicrobial agents in clinic. Methods the clinical data of 260 inpatients in hepatobiliary surgery from January 2010 to October 2013 were analyzed retrospectively. The use of antimicrobial agents and their rationality were analyzed. Results of the 260 patients, 242 had used antibiotics, and the utilization rate of antibiotics was 93.08%, 22 kinds of antibiotics were involved in the 242 cases, cephalosporins and penicillin were used most frequently. Quinolones and niimidazole antibiotics; commonly used in combination, 78 cases were treated with two antibiotics, 67 cases with 3 antibiotics, 53 cases with three antibiotics, 21.900.The most commonly used antibiotics were metronidazole cephalosporin quinolones or aminoglycosides, 260 cases. Only 43 of the patients were tested for pathogens. The inspection rate was 16.54. Conclusion the use of antimicrobial drugs in inpatients with hepatobiliary surgery basically follows the principle of effectiveness and safety, but there are still a few patients with irrational use of drugs, which is worthy of vigilance and improvement.
【作者单位】：齐齐哈尔医学院附属第三医院普外三科;齐齐哈尔市第一医院精神五官分院耳鼻喉科;齐齐哈尔市建华医院乳腺外科;
【基金】：黑龙江科技厅研究基金资助项目(201207856)
【分类号】：R95

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