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105例注射用替加环素用药合理性分析

发布时间:2018-10-23 07:53
【摘要】:目的:加强替加环素使用的规范管理,评价其用药的合理性,为临床合理用药提供参考。方法:抽取我院2014年6月—2015年6月应用注射用替加环素(泰阁)的出院患者病例,从病原学检查、药物敏感性试验、用法用量、疾病类型等方面对105例病例进行评价分析。结果:我院应用注射用替加环素的药物利用指数(DUI)值为1.075;105例病例中,102(97.14%)例行病原学检查,76例(72.38%)有药敏试验结果;65例(61.90%)有2种以上混合感染;83例(79.05%)符合说明书给药剂量。结论:医疗机构需要对注射用替加环素的使用进行严格管理,并对其给药疗程、剂量及处方权限加以控制,防止经验性用药,减少耐药的发生。
[Abstract]:Objective: to strengthen the standardized management of the use of tegacycline, evaluate the rationality of its drug use, and provide reference for clinical rational use of tegacycline. Methods: 105 patients who were discharged with tegacycline (Taige) for injection from June 2014 to June 2015 were evaluated and analyzed in terms of etiological examination, drug sensitivity test, usage dosage, disease type and so on. Results: the drug utilization index (DUI) of tegicycline for injection in our hospital was 1.075% of 105 cases, 102.14% (97.14%) of them were pathologically examined, 76 cases (72.38%) had drug sensitivity test results, 65 cases (61.90%) had two or more mixed infections, 83 cases (79.05%) accorded with the prescribed dosage. Conclusion: medical institutions need to strictly manage the use of tegicycline for injection, and control the course, dosage and prescription authority of the administration of tegacyclin in order to prevent experiential drug use and reduce the occurrence of drug resistance.
【作者单位】: 解放军总医院第一附属医院药剂药理科;
【分类号】:R978.1

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相关期刊论文 前8条

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