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基本药物制度背景下山东省乡镇卫生院慢性病患者处方合理用药情况分析

发布时间:2018-11-20 11:33
【摘要】:目的探讨基本药物制度背景下山东省乡镇卫生院慢性病患者处方合理用药情况。方法 2013年8月对基本药物制度实施前后山东省37家乡镇卫生院的慢性病患者处方进行收集,对其单张处方用药品种数、抗生素处方、注射剂处方以及处方书写清晰性和完整性等合理用药情况进行比较分析,并运用秩和比(RSR)与聚类分析相结合的方法对慢性病患者处方用药合理性进行综合评价。结果基本药物制度实施后,抗生素处方比例由34.0%(50/147)降至20.5%(60/292)、书写清晰处方比例由79.6%(117/147)升至90.4%(264/292),差异均有统计学意义(P0.05);而虽然单张处方药品种数超过5种的处方比例由21.1%(31/147)降至18.5%(54/292)、注射剂处方比例由33.3%(49/147)降至27.4%(80/292)、书写完整处方比例由20.4%(30/147)升至28.4%(83/292),但差异均无统计学意义(P0.05)。在得分聚类中,慢性病患者处方的用药合理性大部分得分在"中"及以上(RSR用药≥0.399),共占79.4%(232/292)。结论基本药物制度实施后,乡镇卫生院慢性病患者处方合理用药情况有所改善,并且处方用药合理性总体较为合理,但仍需进一步提升。
[Abstract]:Objective to explore the rational use of prescription for chronic patients in township health centers in Shandong province under the background of essential drug system. Methods the prescriptions of chronic diseases were collected from 37 township health centers in Shandong province before and after the implementation of the essential drugs system in August 2013. The rational drug use such as injection prescription, clarity and completeness of prescription writing were compared and analyzed, and the rationality of prescribing prescription of chronic disease patients was evaluated synthetically by using rank sum ratio (RSR) and cluster analysis. Results after the implementation of the essential drug system, the proportion of prescriptions for antibiotics decreased from 34.0% (50 / 147) to 20.5% (60 / 292), and the proportion of clearly written prescriptions rose from 79.6% (117 / 147) to 90.4% (264 / 292). The difference was statistically significant (P0.05). And while the proportion of prescriptions with more than five prescriptions on a single prescription fell from 21. 1% (31 / 147) to 18. 5% (54 / 292), the proportion of prescriptions for injections fell from 33. 3% (49 / 147) to 27. 4% (80 / 292). The proportion of complete prescription was increased from 20.4% (30 / 147) to 28.4% (83 / 292), but the difference was not statistically significant (P0.05). In score clustering, most of the scores of prescription rationality of chronic disease patients were "medium" or above (RSR 鈮,

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