研究头孢菌素类药物致临床不良反应调查分析

发布时间：2019-05-16 04:09

【摘要】：目的研究头孢菌素类药物诱发的不良反应类型,探讨相应的处理方法。方法选择本监测中心80例头孢菌素类药物致临床不良反应的患者,对其临床资料开展回顾性分析,分析其不良反应症状,研究不良反应诱发原因和解决办法。结果 80例研究对象中出现变态反应54例,占总研究人数67.5%,其余患者则出现消化系统不良反应或其他不良反应。第二代药物以及第三代药物诱发的不良反应明显比第一代药物和第四代药物高,经静脉滴注治疗诱发的不良反应明显比口服药物和其他方式治疗诱发的不良反应严重。结论选择头孢菌素类药物针对患者开展治疗的过程中,必须要科学选择给药方式,正确挑选抗菌药物品种,加强用药检查及针对性处理。
[Abstract]:Objective to study the types of adverse reactions induced by cephalosporins and to explore the corresponding treatment methods. Methods 80 patients with clinical adverse reactions induced by cephalosporins were selected and their clinical data were analyzed retrospectively. the symptoms of adverse reactions were analyzed and the causes and solutions of adverse reactions were studied. Results of the 80 subjects, 54 (67.5%) had allergic reactions, while the rest had adverse reactions to the digestive system or other adverse reactions. The adverse reactions induced by the second generation drugs and the third generation drugs were significantly higher than those induced by the first generation drugs and the fourth generation drugs. The adverse reactions induced by intravenous drip therapy were significantly more serious than those induced by oral drugs and other treatments. Conclusion in the process of selecting cephalosporins for the treatment of patients, it is necessary to scientifically select the drug delivery methods, correctly select the varieties of antibiotics, and strengthen the examination and targeted treatment of cephalosporins.
【作者单位】：山东省滨州市药品不良反应监测中心;
【分类号】：R978.1

【相似文献】