产妇和新生儿体内重金属水平及其影响因素分析

发布时间：2018-01-09 11:21

本文关键词：产妇和新生儿体内重金属水平及其影响因素分析　出处：《环境与健康杂志》2016年12期 　论文类型：期刊论文

【摘要】：目的了解某地区产妇及新生儿血砷、汞和铅的水平,分析其相关影响因素。方法在某地区随机抽取A、B两所医院,选择2012年4—5月间住院分娩的产妇共226名,采集产妇静脉血和新生儿脐带血,采用电感耦合等离子体质谱法测定全血中砷、汞和铅的浓度,并对产妇进行问卷调查。结果 226对产妇和新生儿血铅浓度范围分别为2.65~67.00μg/L和4.05~70.89μg/L,均低于100μg/L的限值;A医院产妇和新生儿血砷平均浓度分别为1.20μg/L和1.23μg/L,均高于B医院(0.62μg/L和0.71μg/L),差异具有统计学意义(P0.05),血汞和血铅浓度差异均无统计学意义(P0.05);新生儿脐带血中砷、汞和铅浓度与产妇静脉血中同种元素浓度呈显著正相关(P0.01),相关系数分别为0.925、0.832和0.765;多重线性回归分析结果显示,家庭年收入越高,产妇及其新生儿血砷浓度越高(P0.05);产妇文化程度则对血铅水平有显著影响,文化程度越高,产妇及其新生儿血铅浓度越低(P0.05)。结论该地区产妇和新生儿体内砷、汞、铅暴露水平较低,但胎盘对重金属缺乏有效屏障作用,仍应采取有效措施减少产妇和新生儿重金属暴露。
[Abstract]:Objective to understand the area of maternal and neonatal blood arsenic, mercury and lead levels, analysis the related factors. Methods in a A B region were randomly selected, two hospitals, 4 May, a total of 226 maternity hospital delivery in 2012, the acquisition of maternal venous blood and umbilical cord blood, determination of arsenic in whole blood by inductively coupled plasma mass spectrometry, the concentration of mercury and lead, and conducted a questionnaire survey of 226 women. Results on maternal and neonatal blood lead concentrations were 2.65~67.00 g/L and 4.05~70.89 g/L, were lower than the 100 g/L limit; A hospital for maternal and neonatal blood average arsenic concentrations were 1.20 g/L and 1.23 g/L, B were higher than that of the hospital (0.62 g/L and 0.71 g/L), the difference was statistically significant (P0.05). The difference of blood mercury and blood lead concentrations were not statistically significant (P0.05); neonatal umbilical cord blood arsenic, mercury and lead concentration and maternal vein blood concentration in the same static elements A significant positive correlation (P0.01), the correlation coefficients were 0.925,0.832 and 0.765; multiple linear regression analysis showed that family income is higher, maternal and neonatal blood arsenic concentration (P0.05); the women's education level have a significant effect on the blood lead level, the higher the degree of cultural history, maternal and neonatal blood lead the lower the concentration (P0.05). Conclusion the area of maternal and neonatal arsenic, mercury, lead exposure level is low, but the lack of effective barrier function of placenta on heavy metals, still should take effective measures to reduce maternal and neonatal exposure to heavy metals.

【作者单位】：深圳市疾病预防控制中心环境卫生科;深圳市妇幼保健院;
【基金】：原卫生部卫生行业科研专项(201002001)
【分类号】：R114
【正文快照】： 近年来,重金属污染对人体健康造成的危害越来越引起人们的重视。目前有关重金属对人群健康影响的研究,逐渐由高剂量职业暴露[1-2]向低剂量非职业人群的暴露转变,孕妇及胎儿作为高危人群对重金属污染暴露更为敏感。国内外流行病学研究表明[3-4],母亲孕期重金属元素暴露水平影响

【相似文献】