浙江省中年居民体质指数、腰围身高比及膳食脂肪对血清瘦素水平的影响

发布时间：2018-01-17 19:37

本文关键词：浙江省中年居民体质指数、腰围身高比及膳食脂肪对血清瘦素水平的影响　出处：《卫生研究》2017年02期 　论文类型：期刊论文

【摘要】：目的分析浙江省中年居民体质指数(BMI)、腰围身高比(WHtR)及膳食脂肪摄入情况与血清瘦素水平的相关性。方法采用分层随机抽样法,于2014年12月从浙江省抽取4个区县513名30~65岁调查对象,采用3天24小时膳食回顾法进行膳食调查,同时测量其身高、体重、腰围及血清瘦素浓度,分析体格指标及膳食脂肪与瘦素的关系。结果女性血清瘦素水平高于男性(P0.001)。BMI、WHtR与瘦素水平均呈正相关,相关系数男性和女性分别为0.488、0.576和0.453、0.333(P0.0001)。调整WHtR后女性BMI与瘦素水平仍有相关性(r=0.321,P0.0001),调整BMI后男性WHtR与瘦素水平仍有相关性(r=0.354,P0.0001),其余指标相关性消失。偏最小二乘回归结果显示男性WHtR(β=0.27)标准化偏回归系数高于BMI(β=0.21),而女性则为BMI(β=0.26)高于WHtR(β=0.20)。男性总能量、总脂肪、单不饱和脂肪酸(MUFA)与瘦素水平呈负相关(P0.05),而女性多不饱和脂肪酸(PUFA)供能比及(PUFA+MUFA):SFA与瘦素水平呈正相关(P0.05)。对男性调整WHtR、对女性调整BMI,可见男性总脂肪、MUFA仍与瘦素呈负相关(P0.05);女性PUFA供能比与瘦素呈正相关(P0.05),其余指标相关性消失。结论肥胖程度与瘦素水平呈正相关关系,在评价肥胖与瘦素水平关系时,男性WHtR与瘦素水平相关性更强,女性BMI与瘦素水平相关性更强;男性总脂肪摄入量、MUFA与瘦素水平呈负相关,女性PUFA供能比与瘦素水平呈正相关。
[Abstract]:Objective to analyze the correlation between body mass index (BMI), waist height ratio (WHtR), dietary fat intake and serum leptin level in middle-aged residents of Zhejiang Province. In December 2014, 513 subjects aged 30 to 65 years old from 4 districts and counties in Zhejiang Province were selected, and their height and weight were measured by a 3-day 24-hour diet review method. Results Serum leptin level in women was higher than that in men (P 0.001). BMIM WHtR was positively correlated with leptin levels. The correlation coefficient between male and female were 0. 488, 0. 576 and 0. 453, respectively. After adjusting for WHtR, there was still a correlation between BMI and leptin level in female patients (P 0.321, P 0.0001). There was still a correlation between WHtR and leptin level after adjusting BMI (P 0.0001). The results of partial least square regression showed that the standardized partial regression coefficient of WHtR (尾 + 0.27) was higher than that of BMI (尾 = 0.21). BMI0.26 in females was higher than that in WHTR0.200.The total energy and fat in men. Monounsaturated fatty acid (MUFAA) was negatively correlated with leptin level (P 0.05). The ratio of energy supply to energy of polyunsaturated fatty acid (PUFAA) and the level of leptin were positively correlated with the ratio of MUFA):SFA to leptin in women (P 0.05). WHtR was adjusted for men. For women adjusting for BMIs, there was a negative correlation between total fat MUFA and leptin in male patients (P 0.05). There was a positive correlation between the energy supply ratio of PUFA and leptin and the correlation between leptin and other indexes. Conclusion there is a positive correlation between the degree of obesity and the level of leptin, and in the evaluation of the relationship between obesity and leptin level. The correlation between WHtR and leptin level was stronger in male and BMI and leptin level in female. There was a negative correlation between total fat intake and leptin level in men, and a positive correlation between PUFA energy supply ratio and leptin level in women.
【作者单位】：中国疾病预防控制中心营养与健康所卫生计生委微量元素重点实验室;浙江省疾病预防控制中心;
【基金】：国家自然科学基金(No.81372992)
【分类号】：R151.42
【正文快照】： 瘦素为脂肪细胞中分泌的一种蛋白质,可调节机体内能量平衡,减少能量摄入并增加能量消耗[1],但肥胖个体常出现瘦素抵抗,血清瘦素浓度反而上升,这可能是肥胖产生的机制之一[2]。目前国内外关于肥胖与瘦素相关性的研究多将体质指数(body mass index,BMI)作为肥胖指标进行分析和调

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