学龄前儿童尿促性腺激素参考范围社区调查

发布时间：2018-01-27 00:30

  本文关键词： 儿童 学龄前 促性腺激素细胞 尿 黄体生成素 卵泡刺激素 社区　出处：《中国全科医学》2017年20期 　论文类型：期刊论文

【摘要】：目的建立学龄前儿童(3~7岁)尿黄体生成素(ULH)和尿促卵泡素(UFSH)参考范围,观察其性别、年龄特点。方法于2015年5—7月,以江苏省无锡市滨湖区胡埭社区3~7岁学龄前儿童为研究对象,依据2006年世界卫生组织(WHO)生长发育标准,分别计算儿童年龄别身高Z评分(HAZ)、年龄别体质量Z评分(WAZ)和年龄别体质指数(BMI)Z评分(BAZ),3种指标均在-2SD~2SD为符合本调研入组的体格发育标准。睡前排空膀胱,留取过夜晨尿,记录留尿时段,应用免疫化学发光法检测ULH和UFSH,同时检测肌酐(Cr)。结果共纳入1 105例研究对象,其中3岁90例、4岁390例、5岁373例、6~7岁252例。男、女童ULH检出率分别为5.30%(31/585)和11.54%(60/520),UFSH检出率分别为99.83%(584/585)和99.04%(515/520)。男童和女童ULH、UFSH水平比较,差异均有统计学意义(Z=-3.755,P0.001;Z=-19.644,P0.001)。不同年龄女童UFSH水平比较,差异有统计学意义(P0.05);其中5岁、6~7岁UFSH水平均分别低于3岁、4岁(P0.05)。1 105例学龄前儿童中,-2SDHAZ≤0即长期营养状况差者409例,0HAZ2SD即长期营养状况好者696例。长期营养状况差和长期营养状况好者ULH、UFSH水平比较,差异均无统计学意义(Z=-1.018,P=0.309;Z=-1.114,P=0.265)。1 105例学龄前儿童中,-2SDWAZ≤0即短期营养状况差者484例,0WAZ2SD即短期营养状况好者621例。短期营养状况差和短期营养状况好者ULH水平比较,差异无统计学意义(Z=-0.472,P=0.637)。短期营养状况差和短期营养状况好者UFSH水平比较,差异有统计学意义(Z=-1.991,P=0.046)。结论学龄前儿童ULH检出率低,ULH和UFSH参考范围具有性别、年龄特点;学龄前女童UFSH随年龄升高有下降趋势,6岁时趋缓;短期营养状况差的儿童UFSH可升高;而长期营养状况不影响UFSH。
[Abstract]:Objective to establish the reference range of urinary luteinizing hormone (ULH) and urinary follicle stimulating hormone (UFSH) in preschool children, and to observe their sex and age characteristics. Methods from May to July, 2015. According to the World Health Organization (WHO) standards of growth and development in 2006, the 3-year-old 7-year-old preschool children in Hudai Community, Binhu District, Wuxi City, Jiangsu Province, were studied. The age specific height Z score, the age specific weight Z score and the age specific body mass Z score were calculated, and the age specific body mass index (BMIP Z score) and the age specific body mass index (BMIG Z score) were calculated respectively. The three indexes were -2SD-2SD as the standard of physical development. The bladder was emptied before bedtime, the overnight morning urine was taken, and the duration of urine retention was recorded. Immunochemiluminescence assay was used to detect ULH and ULH, and creatinine creatinine was detected simultaneously. Results 1 105 cases were included in this study, 90 cases were 3 years old, 90 cases were 4 390 cases, 5 years old were 373 cases. The detection rate of ULH in males and females was 5.30% 585% and 11.54% 60 / 520 respectively. The detection rate of UFSH was 99.833% 584 / 585) and 99.04515 / 5200.The levels of ULHHUFSH in boys and girls were compared. The difference was statistically significant (P 0.001). The UFSH level of girls of different ages was significantly higher than that of girls of different ages (P 0.05). The level of UFSH at the age of 5 years and 7 years was lower than that of 3 years old and 4 years old, P 0.05 and 1.105 cases of preschool children, including 409 cases whose long-term nutritional status was poor (P < 0). 0HAZ2SD was 696 cases with good long-term nutrition status, and there was no significant difference in ULHHU UFSH level between those with poor long-term nutritional status and those with good long-term nutritional status. Pu 0.309; Among 105 preschool children, 484 cases with short term nutritional status were worse than -2SDWAZ 鈮，

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