不同运动量对绝经后女性心血管疾病危险因素的干预研究

发布时间：2018-02-24 02:46

本文关键词： 绝经后女性 CVD危险因素 10年ICVD风险运动量效关系运动处方　出处：《北京体育大学》2013年硕士论文　论文类型：学位论文

【摘要】：研究目的：绝经后女性体内雌激素水平不断下降,CVD的发病率较绝经前显著增加。本研究通过探索不同运动量对绝经后女性CVD危险因素和风险水平的改善效果,寻找能够替代雌激素替代治疗并防治CVD的方法和途径,提高绝经后女性的生活质量。研究方法：通过问卷调查和计步器筛选出符合条件的受试者,随机分为低量5天组(L-5,19人)、高量5天组(H-5,18人)、低量2天组(L-2,13人)和对照组(12人),运动组进行12周的中等强度的健步走干预,前后测试血清雌激素水平、身体形态指标(体重、BMI、体脂%、腰围、臀围和腰臀比)、血液生化指标(E2、TC、TG、LDL-C、HDL-C和空腹血糖)和血管机能指标(安静心率、SBP/DBP、baPWV),并使用“国人ICVD十年发病危险评估方法”评估10年ICVD的风险,综合评价不同运动量对CVD相关危险因素和风险的干预效果。研究结果：三个月后,L-5组的SBP、baPWV、HDL-C口10年ICVD风险得到显著改善；L-2组的SBP、baPWV得到显著改善；H-5组的腰围、SBP, DBP、baPWV、 TG、TC、HDL-C、LDL-C、TC/HDL-C和10年ICVD风险得到显著改善。对照组的体脂%、TC非常显著增加,E2非常显著下降,LDL-C、TC/HDL-C、10年ICVD对风险显著增加。研究结论：1)绝经后女性按照150%ACSM推荐量、每周5天的运动频率进行运动,可以对CVD风险因素起到全面的改善作用,降低10年ICVD的绝对风险度。2)运动量与SBP、baPWV、HDL-C存在着剂量-效应关系,并且改善的幅度随着运动量的增加而增加。
[Abstract]:Objective: the incidence of estrogen in postmenopausal women was significantly higher than that of premenopausal women. This study was conducted to explore the effects of different levels of exercise on the risk factors and risk levels of CVD in postmenopausal women. In order to improve the quality of life of postmenopausal women, to find ways to replace estrogen replacement therapy and prevent and treat CVD. Methods: the eligible subjects were selected by questionnaire survey and pedometer. The rats were randomly divided into low dose group (n = 19), high dose group (n = 18), low dose group (n = 13) and control group (n = 12). Body shape indexes (body weight, body fat, waist circumference, hip circumference and waist-to-hip ratio, blood biochemistry, TGG, LDL-CU HDL-C and fasting blood glucose) and vascular function indexes (quiet heart rate and SBP / DBP BBA PWV) were used to assess the risk of ICVD for 10 years using the "Ten years risk Assessment method for ICVD in Chinese". Comprehensive evaluation of intervention effects of different exercise doses on risk factors and risk of CVD. Results: after 3 months, the ICVD risk of SBPBA PWV in group L-5 was significantly improved after 10 years of HDL-C exposure. The SBPBA PWV of group L-2 significantly improved the waist circumference of SBP, DBPBA PWV, TGTCU HDL-CLDL-C and TC- HDL-C of L-2 group. The risk of ICVD was significantly improved in 10 years in the control group, and significantly increased in the control group, and decreased significantly in the control group (P < 0.05). The risk was significantly increased in the control group compared with the control group, and the risk was significantly increased after 10 years of ICVD. Conclusion: (1) exercise frequency 5 days a week, recommended by 150SM, can improve risk factors of CVD in postmenopausal women. Decrease of absolute risk degree of ICVD for 10 years. 2) there was a dose-effect relationship between the amount of exercise and HDL-C, and the range of improvement increased with the increase of the amount of exercise.
【学位授予单位】：北京体育大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：G804.3;R173

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