三种葡萄糖酸氯己定复方手消毒剂杀菌效果和临床实验研究

发布时间：2018-03-10 03:13

本文选题：洗手　切入点：手卫生　出处：《中华医院感染学杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的测试三种葡萄糖酸氯己定复方手消毒剂临床消毒效果,为临床科室提供安全有效的手消毒剂。方法根据《消毒技术规范》对三种葡萄糖酸氯己定复方手消毒剂进行检测。结果三种葡萄糖酸氯己定复方手消毒剂pH值,泡沫抗菌洗手液为6.50、泡沫外科消毒剂为6.38,外科手消毒凝胶为6.70,有效成分葡萄糖酸氯己定含量分别为0.185%、1.23%、1.19%,泡沫和凝胶手消毒液乙醇含量分别为:38.2%、54.7%,泡沫抗菌洗手液细菌总数、大肠杆菌、金黄色葡萄球菌、真菌菌落符合国家标准要求;泡沫抗菌洗手液对大肠杆菌杀灭对数值均5.00,对金黄色葡萄球菌杀菌不合格;泡沫外科消毒剂对大肠杆菌、金黄色葡萄球菌作用1.5min,对白念珠菌、铜绿假单胞菌作用3.0min,可达到消毒合格;外科手消毒凝胶大肠杆菌、金黄色葡萄球菌、白念珠菌、铜绿假单胞菌作用1.0min,可达到消毒合格;使用葡萄糖酸氯己定泡沫抗菌洗手液后用葡萄糖酸泡沫外科消毒剂或葡萄糖酸氯己定外科手消毒凝胶5ml,消毒作用3min,对临床科室医务人员手上自然菌杀灭对数1.0,手上残留菌数1cfu/cm2。结论三种葡萄糖酸氯己定复方手消毒剂消毒配合使用消毒效果达到临床消毒要求,可以在临床科室使用。
[Abstract]:Objective to test the clinical efficacy of three kinds of chlorhexidine gluconate compound hand disinfectants. Methods three kinds of chlorhexidine gluconate compound hand disinfectants were detected according to the Technical Specification for Disinfection. Results the pH value of the three compound hand disinfectants was determined. Foam antibacterial hand sanitizer 6.50, foam surgical disinfectant 6.38, surgical hand disinfectant 6.70, active ingredient chlorhexidine gluconate 0.185 and 1.23um 1.19.The ethanol content of foam and gel hand disinfectant was 54.70.The total number of bacteria in foam antibacterial hand sanitizer was 54.7, respectively. Escherichia coli, Staphylococcus aureus, fungal colony meet the national standard requirements; foam antibacterial hand sanitizer to Escherichia coli logarithmic value 5.00, not qualified for Staphylococcus aureus sterilization; foam surgical disinfectant for Escherichia coli, Staphylococcus aureus exposed to 1.5 min, Candida albicans and Pseudomonas aeruginosa exposed to 3.0 mins, the surgical hands disinfection gel Escherichia coli, Staphylococcus aureus, Candida albicans and Pseudomonas aeruginosa could be sterilized for 1.0 min. After the use of chlorhexidine gluconate foam antibacterial hand sanitizer, the surgical disinfectant of gluconic acid foam or chlorhexidine gluconate surgical hand disinfection gel was used to disinfect the gel for 5 ml for 3 min. The natural bacteria on the hands of the medical staff in clinical departments were killed by logarithm 1.0. Conclusion the disinfection effect of three kinds of chlorhexidine gluconate compound hand disinfectant combined with disinfection can meet the requirement of clinical disinfection. It can be used in clinical department.
【作者单位】：武警工程大学医院医院感染管理科;
【分类号】：R187

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