焦炉工人血压与神经行为损伤调查分析

发布时间：2018-03-14 01:29

本文选题：焦炉工人　切入点：职业暴露　出处：《毒理学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨焦炉工人血压变化对神经行为的影响,为制定合理的防控措施提供一定的理论依据。方法选取山西某焦化厂198名焦化作业工人为暴露组,该厂145名非焦化作业工人为对照组,使用统一的调查表收集个人信息,静息状态下检测血压3次,采用WHO推荐的神经行为核心测试组合(NCTB)对研究对象的情感状态和神经行为功能进行测试。结果对照组中血压异常的工人数字跨度(倒序、总体)、数字译码和目标追踪(正确数、总数)得分显著低于血压正常的工人,差异有统计学意义(P0.05)。血压正常的工人中,暴露组工人紧张-焦虑、反应时间等13项指标得分显著低于对照组,差异均有统计学意义(P0.05)。而血压异常的工人中,暴露组工人愤怒-敌意、平均反应时间、最快反应时间、最慢反应时间、数字跨度(顺序、倒序、总体)、数字译码和目标追踪(正确数、错误数、总数)得分显著低于对照组,差异有统计学意义(P0.05)。多元线性回归分析显示:神经行为得分与焦炉环境暴露和工人血压水平呈负相关,且数字译码和目标追踪(正确数、总数)得分与暴露和血压的相乘项呈现负相关。结论血压升高可能影响焦炉工人的短期听记忆力、视觉记忆和运动速度以及手部运动速度和准确性,焦炉环境则会影响工人的各项神经行为,且两因素对视觉记忆和运动速度以及手部运动速度和准确性存在负交互作用。
[Abstract]:Objective to investigate the effect of changes in blood pressure on neurobehavioral behavior of coke oven workers, and to provide a theoretical basis for making reasonable prevention and control measures. Methods 198 coking workers in a coking plant in Shanxi Province were selected as exposure group. In the control group, 145 non-coking workers collected personal information with a unified questionnaire, and measured their blood pressure 3 times in a resting state. The emotional state and neurobehavioral function of the subjects were tested with the neurobehavioral core test combination (NCTB) recommended by WHO. Results in the control group, the workers with abnormal blood pressure had a number span (reverse order, total inversion, digital decoding and target tracking). The total score was significantly lower than that of the workers with normal blood pressure, the difference was statistically significant (P 0.05). In the workers with normal blood pressure, the scores of 13 indexes, such as tension, anxiety, reaction time and so on, were significantly lower in the exposed group than in the control group. The differences were statistically significant (P 0.05). Among the workers with abnormal blood pressure, the exposed workers were angry-hostile, average reaction time, fastest reaction time, slowest response time, digital span (order, reverse order). The scores of total number, digit decoding and target tracking (correct number, error number, total) were significantly lower than those in the control group. Multiple linear regression analysis showed that there was a negative correlation between neurobehavioral scores and coke oven exposure and blood pressure level of workers, as well as digit decoding and target tracking (correct number). Conclusion elevated blood pressure may affect short-term auditory memory, visual memory and motor speed, and the speed and accuracy of hand movement in coke oven workers. The coke oven environment will affect the neural behavior of workers, and the two factors have negative interaction on visual memory and movement speed, hand movement speed and accuracy.
【作者单位】：山西医科大学公共卫生学院卫生毒理学教研室;山西焦化集团有限公司职业病防治所;
【基金】：国家自然科学基金(30872137) 山西省优势和特色重点学科建设经费
【分类号】：R135

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