富硒玉米对中老年血硒、空腹血糖及谷胱甘肽过氧化物酶的影响

发布时间：2018-03-14 12:25

本文选题：硒　切入点：富硒食品　出处：《卫生研究》2015年03期 　论文类型：期刊论文

【摘要】：目的研究富硒玉米对中老年人血硒、空腹血糖(FPG)及谷胱甘肽过氧化物酶(GPx)活性的影响。方法 120名51~84岁的研究对象随机分为普通玉米组和富硒玉米组,每日食用15 g玉米粉(富硒玉米含硒50μg,普通玉米含硒0.2μg)10个月,比较干预前后指标的变化。结果两组间性别、年龄、BMI、基础血硒、FPG以及GPx活性无显著差异。干预后两组血硒水平均显著升高,富硒玉米组(129.20±29.47)μg/L显著高于普通玉米组(101.06±29.44)μg/L(P0.01),富硒玉米组的血硒增值与基础血硒水平呈负相关(r=0.41,P0.05)。干预后FPG无显著改变,但两组GPx活性均显著升高,富硒玉米组GPx活性的增值(80.12±93.31)显著高于普通玉米组(43.35±69.01)(P0.01),而且富硒玉米组血硒水平与GPx活性呈显著正相关(r=0.42,P0.05)。结论富硒玉米干预显著提高了中老年人群血硒水平和GPx活性,对FPG影响较小。
[Abstract]:Objective to study the effects of selenium enriched corn on the activities of blood selenium, fasting blood glucose (FPG) and glutathione peroxidase (Glutathione peroxidase) in middle-aged and elderly people. Methods 120 subjects aged 51 to 84 years were randomly divided into normal corn group and selenium-enriched corn group. 15 g corn meal (50 渭 g selenium enriched corn and 0.2 渭 g selenium in common corn) were consumed daily for 10 months. The changes of indexes before and after intervention were compared. There was no significant difference in the activities of BMI, FPG and GPx between the two groups, but the levels of blood selenium in the two groups were significantly increased after intervention. Compared with the normal corn group (101.06 卤29.44) 渭 g 路L ~ (-1) P ~ (0.01), the blood selenium increment in the selenium-enriched corn group was negatively correlated with the basic blood selenium level. There was no significant change in FPG after the intervention, but the activity of GPx was significantly increased in both groups. The increment of GPx activity in the selenium-enriched corn group was 80.12 卤93.31), which was significantly higher than that in the normal corn group (43.35 卤69.01), and there was a significant positive correlation between the blood selenium level and the GPx activity in the selenium-enriched corn group. It has little effect on FPG.
【作者单位】：苏州市疾病预防控制中心;苏州大学医学部公共卫生学院营养与食品卫生教研室;中国科学技术大学苏州研究院;苏州市金门中医诊所;
【基金】：苏州市科技支撑计划(No.SS201222) 江苏省卫生厅医学科研课题(No.H201040) 江苏省预防医学科研课题(No.Y2012078)
【分类号】：R151

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