广东2006—2015年围产儿出生缺陷监测分析

发布时间：2018-03-15 07:11

本文选题：出生缺陷　切入点：围产儿　出处：《中国公共卫生》2017年11期 　论文类型：期刊论文

【摘要】：目的分析广东省2006—2015年出生缺陷变化趋势及相关因素,为科学防控出生缺陷、合理评价出生缺陷防控项目实施效果提供参考依据。方法对2006—2015年广东省出生缺陷监测数据进行回顾性描述和趋势分析。结果 2006—2015年广东省总平均出生缺陷发生率为276.80/万(56 040/2024 583),高于其他省份,并有逐年增高趋势(Z=1.99,P=0.04)。缺陷儿在性别(男性33 629例,女性21 976例,性别不明435例,χ~2=758.24,P0.001)、产母常住地(城镇26 896例,乡村28 981例,χ~2=35.30,P0.001)、产母年龄等方面差异有统计学意义。广东省发病率较高的出生缺陷主要是先天性心脏病、葡萄糖-6-磷酸脱氢酶缺乏症(G6PD缺乏症)、胎儿水肿综合征、多指(趾)、马蹄内翻足,2015年并指(趾)取代马蹄内翻足进入前5位出生缺陷。结论广东省出生缺陷监测发生率较高,需要加强三级防控措施,减少出生缺陷,提高人口素质。
[Abstract]:Objective to analyze the trend and related factors of birth defects in Guangdong Province from 2006 to 2015, so as to prevent and control birth defects scientifically. Methods retrospective description and trend analysis of birth defects monitoring data from 2006 to 2015 in Guangdong Province were carried out. Results the total average incidence of birth defects in Guangdong Province from 2006 to 2015 was analyzed. For 276.80 / 10,000, 56 040/2024 583, which is higher than other provinces, There is an increasing trend of increasing year by year. The defect children are in the sex (male 33,629, female 21,976, sex unknown 435, 蠂 ~ (2 758.24) P 0.001), and the mother's permanent residence (urban 26896). There were significant differences in birth age between 28 981 rural patients with 蠂 2, 35.30 and P 0.001.The main birth defects in Guangdong Province were congenital heart disease, G6PD deficiency, fetal edema syndrome, G6PD deficiency, and G6PD deficiency of Glucose-6-phosphate dehydrogenase deficiency. In 2015, the phalanx equinovarus foot replaced the equinovarus foot to the top 5 birth defects. Conclusion the incidence of birth defects monitoring in Guangdong Province is high, so it is necessary to strengthen the three-level prevention and control measures to reduce birth defects and improve the quality of the population.
【作者单位】：广东省妇幼保健院保健部;广东省妇幼保健院院长室;
【基金】：2015年度广东省医学科研基金(C2015009)
【分类号】：R174

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