绝经女性中心型肥胖及其前期与高血糖发病风险关系的研究

发布时间：2018-03-16 20:00

本文选题：腰围　切入点：中心型肥胖　出处：《卫生研究》2016年02期 　论文类型：期刊论文

【摘要】：目的探讨绝经女性中心型肥胖及其前期与高血糖发病风险的关系。方法调查苏州工业园区2014年进行慢性病社区综合防治的35岁以上健康自然绝经12个月以上的女性323人,测量血压、身高、体重、腰围,采血测定空腹血糖(FPG)、糖化血红蛋白(HbA1c)、血脂水平。根据腰围诊断中心型肥胖及中心型肥胖前期,根据FPG和HbA1c诊断高血糖。结果绝经女性中心型肥胖及前期占31.0%。腰围水平与FPG(r=0.18,P0.01)及HbA1c(r=0.20,P0.01)呈正相关。用FPG和HbA1c诊断高血糖,检出率分别为34.4%和83.9%。用FPG诊断高血糖,中心型肥胖及前期人群高血糖检出率以及发病风险与正常人群差异无统计学意义(31.8%vs 40.0%,P=0.076)。用HbA1c诊断高血糖,中心型肥胖及前期人群高血糖检出率显著高于正常人群(91.0%vs 80.7%,P=0.020)。多因素Logistic回归分析显示人群患高血糖的OR=2.46(95%CI 1.07~5.62)(P=0.034)。结论中心型肥胖以及中心型肥胖前期可能是高血糖发生的危险因素。
[Abstract]:Objective to investigate the relationship between menopausal women's central obesity and the risk of hyperglycemia. Methods in 2014, 323 women aged over 35 years old and over 12 months of natural menopause were investigated in Suzhou Industrial Park for the comprehensive prevention and treatment of chronic diseases. Blood pressure, height, weight, waist circumference were measured, fasting blood glucose level (FPGN), HbA1cn (HbA1cU), and blood lipid levels were measured. According to waist circumference, central obesity and central obesity were diagnosed. FPG and HbA1c were used to diagnose hyperglycemia. Results the prevalence of central obesity in postmenopausal women was 31. 0. The waist circumference level was positively correlated with FBG 0.18 and HbA1ctrocardia 0.20 and P0.01. The detection rates of hyperglycemia were 34.4% and 83.9 for FPG and HbA1c, respectively. FPG was used to diagnose hyperglycemia. There was no significant difference in the detection rate of hyperglycemia and the risk of onset between the central obesity group and the early stage population, and there was no significant difference in the incidence of hyperglycemia between the central obesity group and the early stage population. There was no significant difference between the two groups. The detection rate of hyperglycemia was significantly higher in central obesity and precancerous population than that in normal controls (91.0 vs 80.7). Multivariate Logistic regression analysis showed that OR=2.46(95%CI 1.075.62P0.0340.Conclusion the central obesity and the early stage of central obesity may be the risk factors for the occurrence of hyperglycemia.
【作者单位】：苏州大学公共卫生学院营养与食品卫生教研室;苏州工业园区疾病防治中心;
【基金】：江苏省预防医学科研课题立项(No.Y2012024)
【分类号】：R173

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