燕麦膳食纤维对食源性肥胖小鼠降脂减肥作用研究

发布时间：2018-03-18 08:00

本文选题：燕麦　切入点：膳食纤维　出处：《中国粮油学报》2015年09期 　论文类型：期刊论文

【摘要】：深入研究水溶性及水不溶性燕麦膳食纤维降脂减肥作用的效果。60只昆明小鼠,饲喂高脂饲料构建肥胖模型后,分别饲喂添加低、高剂量(7.33、14.67 g·kg-1(BW)·d-1)的燕麦水溶性(SDF)水不溶性(IDF)膳食纤维的高脂饲料作为试验组,另设饲喂普通饲料和高脂饲料作为正常对照组和肥胖模型组。测定相关指标的变化。与肥胖模型组相比,肥胖小鼠在食用燕麦膳食纤维以后,Lee’s指数显著下降(P0.05),IDF效果最好;腹腔脂肪堆积显著减少(P0.05),激素敏感性脂肪酶显著升高(P0.05),同时胰岛素分泌减少促甲状腺激素分泌增加(P0.05),SDF作用效果高于IDF(P0.05);小鼠肝脏系数、肝脏总胆固醇(TC)和三酰甘油(TG)水平显著降低(P0.05),肝脏肝酯酶(HL)和脂蛋白酯酶(LPL)活性升高(P0.05),但是与正常组对照小鼠相比仍有显著差异(P0.05),SDF效果比IDF更显著。燕麦SDF和IDF都具有降脂减肥作用,存在剂量效应,但作用途径不同。
[Abstract]:The effects of water-soluble and water-insoluble oat dietary fiber on reducing fat and reducing weight were studied in 60 Kunming mice. The high fat diet with high dose of 7.33 ~ 14.67 g 路kg ~ (-1 BW) 路d ~ (-1) oat water-soluble SDF) was used as the experimental group. In addition, normal diet and high fat diet were used as normal control group and obesity model group. The changes of relative indexes were determined. Compared with the obese model group, the obese mice had the best effect after eating oat dietary fiber. Abdominal fat accumulation was significantly reduced, hormone sensitive lipase was significantly increased, and insulin secretion was decreased. The effect of SDF was higher than that of IDFG P0.05.The liver coefficient of mice was higher than that of IDFG. The levels of liver total cholesterol (TCC) and triacylglycerol (TG) decreased significantly (P 0.05), while liver esterase (HLL) and lipoprotein esterase (LPL) activities increased, but there was still a significant difference compared with the control group. The effect of SDF and IDF in oats was higher than that of IDF. They all have the effect of reducing fat and losing weight. There is dose effect, but the way of action is different.
【作者单位】：郑州轻工业学院食品与生物工程学院;
【基金】：国家自然科学基金(31271854)
【分类号】：R151

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