挤压超微粉碎刺梨果渣对糖尿病小鼠血糖及组织抗氧化活性的影响

发布时间：2018-04-10 05:40

本文选题：刺梨果渣　切入点：挤压超微粉碎　出处：《食品科技》2017年10期

【摘要】：采用小鼠尾静脉注射四氧嘧啶复制糖尿病小鼠模型,以试验组与对照组悬浮液分别灌胃给药,跟踪测定小鼠体重、眼球取血测定空腹血糖含量,以及心、肝、肾组织氧化水平相关指标。试验发现,与模型组相比,经14 d喂养,小鼠高、中、低剂量对照组和试验组体重均增长迅速(P0.05),高、中剂量试验组体重增长水平与对照组相比有差异(P0.05)。第7天与第14天,对照组和试验组血糖值均降低,与模型组差异显著(P0.05),其中高剂量试验组效果最佳,血糖值比模型组降低了36.21%和59.98%(P0.01),且试验组血糖降低水平大于对照组(P0.05)。同时,通过测定各组小鼠心、肝、肾氧化指标表明,2种果渣均能明显升高T-AOC、SOD并降低MDA(P0.01)。结果表明,挤压超微粉碎刺梨果渣与原料果渣对四氧嘧啶所致糖尿病小鼠有降低血糖的作用,其中挤压超微粉碎处理降糖作用较优。刺梨果渣能较好降血糖及改善氧化应激作用,有助于缓解糖尿病症状。
[Abstract]:The diabetic mice model was established by injecting alloxan into tail vein of mice. The mice in the experimental group and the control group were administrated intragastrically respectively. The body weight of the mice was measured, the fasting blood glucose content was measured by eyeball blood sampling, and the heart and liver were measured.Related indexes of renal tissue oxidation level.It was found that compared with the model group, after 14 days of feeding, the body weight of the mice in the high, middle and low dose control group and the experimental group all increased rapidly (P 0.05), and the weight increase level of the medium dose group was higher than that of the control group. There was a difference between the medium dose group and the control group.On the 7th and 14th days, the blood glucose levels in the control group and the experimental group were significantly lower than those in the model group (P 0.05). The high dose test group had the best effect. The blood glucose value of the high dose group was 36.21% and 59.98% lower than that of the model group, and the level of blood glucose in the experimental group was higher than that in the control group.At the same time, the oxidation indexes of heart, liver and kidney of each group of mice were determined. The results showed that both kinds of fruit dregs could significantly increase T-AOC SOD and decrease MDA-P0.01.The results showed that the superfine grinding of Rosa roxburghii and the raw residue had the effect of reducing blood glucose in diabetic mice induced by alloxan.Rosa roxburghii fruit residue can lower blood sugar and improve oxidative stress, which is helpful to relieve the symptoms of diabetes.
【作者单位】：中山大学中山医学院;贵州大学酿酒与食品工程学院;
【基金】：贵州省科技重大专项(黔科合重大专项字[2013]6006) 贵州省教育厅科学基金项目(黔教合KY字[2015]366)
【分类号】：R151;TS209

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