米索前列醇不同给药方式联合宫腔吸引管在剖宫产术后无痛人流中的应用

发布时间：2018-04-17 19:46

本文选题：米索前列醇 + 无痛人流　；参考：《中国药房》2015年33期

【摘要】：目的:探讨米索前列醇不同给药方式联合宫腔吸引管在剖宫产术后无痛人流中的应用。方法:214例剖宫产术后无痛人流患者随机分为A组(71例)、B组(71例)、C组(72例)。所有患者均给予常规静脉麻醉后,A组患者术前2 h给予米索前列醇0.6mg,口服;B组患者术前3 h给予米索前列醇片0.2 mg,研粉后置入阴道后穹窿;C组患者不给予相关药物。各组患者均使用一次性宫腔吸引管。观察各组患者的镇静效果、宫颈扩张效果、手术时间、术中出血量、苏醒时间、异丙酚用量、并发症发生情况及不良反应发生情况。结果:A组患者手术时间、术中出血量B组C组,差异有统计学意义(P0.05),A组患者苏醒时间、异丙酚用量B、C组,差异均有统计学意义(P0.05),但B、C两组间比较差异无统计学意义(P0.05);A、B组患者镇静、宫颈扩张总有效率显著高于C组,差异有统计学意义(P0.05),但A、B两组间比较差异无统计学意义(P0.05);A组患者并发症发生率B组C组,差异有统计学意义(P0.05)。各组患者不良反应发生率比较,差异无统计学意义(P0.05);结论 :口服或阴道给予米索前列醇联合宫腔吸引管治疗剖宫产术后无痛人流的疗效和安全性均相当,但口服给药可减少麻醉药物用量,减少术中出血量,缩短手术时间。
[Abstract]:Objective: to investigate the application of misoprostol combined with intrauterine suction tube in painless abortion after cesarean section.Methods 214 cases of painless abortion after cesarean section were randomly divided into group A (n = 71) and group B (n = 71).All the patients were given misoprostol 0.6 mg 2 h before operation in group A after routine intravenous anesthesia, and 0.2 mg of misoprostol tablets were given to patients in group B 3 h before operation.All patients were treated with disposable uterine cavity suction tube.The sedation effect, cervical dilatation, operative time, intraoperative bleeding, recovery time, propofol dosage, complications and adverse reactions were observed.Results the time of operation and intraoperative bleeding in group B were significantly different from those in group A (P 0.05), and propofol dosage was used in group C.The difference was statistically significant (P 0.05), but there was no significant difference between the two groups. The total effective rate of cervical dilatation in group B was significantly higher than that in group C.The difference was statistically significant (P 0.05), but there was no significant difference between the two groups. The incidence of complications in group B was significantly higher than that in group C (P 0.05).Conclusion: the efficacy and safety of oral or vaginal misoprostol combined with intrauterine suction tube in the treatment of painless abortion after cesarean section are similar.But oral administration can reduce the dosage of anesthetic, reduce the amount of intraoperative bleeding and shorten the operation time.
【作者单位】：大冶有色金属集团控股有限公司总医院;
【分类号】：R169.42

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