九江地区2010与2015年入托入学儿童麻疹抗体水平

发布时间：2018-04-19 08:13

本文选题：麻疹 + 抗体　；参考：《中国学校卫生》2017年01期

【摘要】：目的了解江西省九江地区2010年与2015年2~10岁入托入学儿童麻疹抗体水平,为探讨阻断麻疹传播策略提供参考。方法于2010年和2015年开展学龄儿童麻疹免疫水平血清流行病学调查,分离血清后采用酶联免疫吸附试验检测抗体。结果 2015年共调查儿童612名,2010年共调查儿童774名,各年龄组麻疹—风疹二联疫苗(MR)、麻疹—腮腺炎—风疹三联疫苗(MMR)接种率均超过95%;城郊儿童麻疹Ig G抗体水平均低于城区,差异均有统计学意义(P值均0.05)。2015年的城郊、城区、男童、女童和2岁组儿童的GMT均低于2010年,差异均有统计学意义(P值均0.05)。2015年2岁儿童的抗体阳性率为67.4%(95%CI=58.7%~72.3%),低于2010年的78.5%(95%CI=73.8%~83.9%)(χ~2=45.491,P0.05)。3~6岁组麻疹抗体阳性率较2岁组上升,但随后抗体阳性率出现下降趋势。结论应进一步加强郊区儿童、2岁组儿童麻疹监测,以及儿童入学入托接种证查验工作,预防麻疹在幼儿园和小学的流行。
[Abstract]:Objective to investigate the measles antibody levels of children aged 2 ~ 10 years in Jiujiang district of Jiangxi province in 2010 and 2015, and to provide a reference for the strategy of interdicting measles transmission.Methods A seroepidemiological survey was carried out in 2010 and 2015 on the measles immunization level of school children. The serum was isolated and tested for antibodies by enzyme-linked immunosorbent assay (Elisa).Results 612 children were investigated in 2015 and 774 children were investigated in 2010. The coverage rates of measles rubella vaccine MRN, measles mumps and rubella vaccine MMRs in all age groups exceeded 95%, and the measles IgG antibody level of children in suburbs was lower than that in urban areas.The GMT of suburb, urban area, boys, girls and children aged 2 years in 2015 was lower than that in 2010.In 2015, the positive rate of measles antibody in children aged 2 years was 67.4g / 95, 58.7% and 72.3% respectively, which was lower than that in 2010 (78.5%) and 73.89% (蠂 ~ 25.491P 0.05 .36 years old). The positive rate of measles antibody in children aged 2 years was higher than that in the group of 2 years old, but the positive rate of measles antibody had a downward trend.Conclusion the surveillance of measles in children aged 2 years in suburban areas and the examination of children's school attendance certificate should be strengthened to prevent the prevalence of measles in kindergartens and primary schools.
【作者单位】：江西省九江市浔阳区疾病预防控制中心;
【分类号】：R186

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