生物组织电学特性及其在电磁场曝露后的变化研究

发布时间：2018-04-26 16:27

本文选题：电磁场 + 生物效应　；参考：《电子科技大学》2012年博士论文

【摘要】：当前，环境电磁污染日益严重，引起了全球众多卫生机构的重视，如何确定环境中存在的电磁辐射对于人体健康的影响是各学者关注的主要问题之一，电磁场生物效应的发生与发展与电磁场本身的特性以及生物组织的电磁学性质密切相关，而生物组织的电磁学性质又随着电磁场频率的变化而变化，因此，很有必要对于不同电磁辐射作用下生物组织的电磁学特性进行研究，在这篇论文中，我们研究了静磁场、红外辐射、极低频电磁场照射作用前后大鼠不同组织的电学特性的变化，分析了以上不同类型电磁场对于生物体产生的一些具体的影响，对于不同类型的电磁场曝露作用的大鼠组织进行红外光谱测量，分析了不同电磁场曝露作用对于大鼠组织结构的改变进行了研究，，并对于电磁辐射影响健康的机理及其防护策略进行了初步的研究。本论文的主要研究工作可概括为以下几部分：第一，主要对于15个大鼠活性组织在10kHz-10MHz的频率范围内的电学特性进行了测量，并利用εr10k/εr10M数值评价了不同组织的含水量的大小，同时还对于大鼠血液，睾丸和脑组织电学特性随离体后半小时内随时间的变化关系进行了测量。并对于上述诸测量结果进行了分析，研究了不同组织电学特性的差异及其原因。研究结果表明不同的生物组织具有不同的电学特性，不同组织电学特性的差异较大，一些组织的含水量较高，因此电导率偏高，含水量较高的组织的εr10k/εr10M数值也较大。大鼠电磁敏感组织电学特性随时间的变化的结果是离体后其介电常数在不同频段表现的变化趋势基本相同，即随着离体时间的增大，其相对介电常数变小，并且变化幅度随着时间增大而变小。电导率在不同频点的变化趋势也基本相同，大多数是随着离体时间的增大而减小。第二，在已经测得的生物活性组织电学特性的基础上，利用测量结果计算了外场在体内的耦合结果和不同频率电磁辐射热效应的发生规律，认为外场频率越低的电磁波穿透生物组织的能力就越强。第三，通过电磁场曝露作用对大鼠电磁敏感组织的电学特性的改变研究了电磁场与生物体的相互作用的特点，其中重点研究静磁场，工频电磁场以及红外线等场曝露作用前后大鼠电磁敏感组织的电学特性的改变情况。通过研究发现经过电磁场曝露一定时间作用以后，大鼠敏感组织的电学特性产生一定的变化，其中有部分频率点的变化较大，实验组与对照组相比具有显著差异。文章进一步结合电磁场理论分析了电磁场曝露作用导致大鼠组织电学特性变化的可能的机理。第四，通过红外光谱技术分析静磁场、工频电磁场和红外线辐射曝露对于大鼠敏感组织红外光谱特征的影响，研究各类电磁场曝露作用对于血液、神经、生殖系统的影响，分别测量了大鼠在接受一定时间的电磁场曝露后其血液，睾丸和脑组织的红外光谱数据，并分析了实验组和对照组在峰位、峰形以及二阶导数谱的区别及其可能产生的原因，以期能够明确电磁辐射的遗传损伤位点和效应机制，为电磁辐射危害的医学防护提供依据。第五，研究红外场曝露对于疾病模型大鼠的影响。主要利用红外场曝露高血糖大鼠考查红外场曝露对于高血糖大鼠血液组织电学特性以及红外光谱特性等方面的影响来探讨红外线曝露对于高血糖大鼠产生影响的机理，研究结果认为红外场曝露有助于高血糖大鼠的恢复，电学特性和红外光谱特性的测试结果表明红外场曝露有助于高血糖大鼠接近于正常大鼠。
[Abstract]:At present, environmental electromagnetic pollution is becoming more and more serious, which has aroused the attention of many health institutions all over the world. How to determine the influence of electromagnetic radiation on human health is one of the main concerns of various scholars. The occurrence and development of the biological effect of electromagnetic field and the characteristics of the electromagnetic field itself and the electromagnetics of biological tissues are closely related. The electrical and magnetic properties of biological tissues vary with the frequency of electromagnetic fields. Therefore, it is necessary to study the electromagnetics characteristics of biological tissues under different electromagnetic radiation. In this paper, we studied the electromagnetics of the different tissues of rats before and after the effect of static magnetic field, infrared radiation, and extremely low frequency electromagnetic field irradiation. The specific effects of different types of electromagnetic fields on organisms were analyzed. The infrared spectrum of rats with different types of electromagnetic field exposure was measured. The changes of tissue structure in rats were analyzed by different electromagnetic field exposure, and the effects of electromagnetic radiation on health were also studied. The main research work of this paper can be summarized as follows:
First, the electrical properties of the active tissues of 15 rats were measured in the frequency range of 10kHz-10MHz. The water content of different tissues was evaluated using the value of epsilon r10k/ e r10M, and the electrical characteristics of the rat blood, testis and brain tissue were measured with time in the half hour after the body. The results of these measurements are analyzed and the differences and reasons of electrical characteristics of different tissues are studied. The results show that different biological tissues have different electrical characteristics, the differences in electrical properties of different tissues are larger, the water content of some tissues is higher, so the electrical conductivity is high and the high water content of the tissue is r10k/ epsilon R1 The electrical properties of the electromagnetically sensitive tissues of the rats are also larger. The electrical properties of the electromagnetically sensitive tissues of rats are changed with time. The change trend of the dielectric constant in different frequency bands is basically the same, that is, the relative dielectric constant becomes smaller with the increase of the time, and the amplitude of the change decreases with the increase of time. The change of electrical conductivity at different frequency points is the same. The potential is basically the same, and most of them decrease with the increase of in vitro time.
Second, on the basis of the electrical properties of the bioactive tissues that have been measured, the results of the coupling in the body and the law of the thermal effects of electromagnetic radiation at different frequencies are calculated by the measurement results. The stronger the ability of the electromagnetic wave to penetrate biological tissues is that the lower the field frequency is.
Third, the electrical characteristics of electromagnetically sensitive tissues of rats were changed by electromagnetic field exposure. The characteristics of the interaction between the electromagnetic field and the organism were studied. The changes in the electrical properties of the electromagnetically sensitive tissues of rats before and after the exposure to the magnetic field, the power frequency electromagnetic field and the infrared field were focused on. After exposure of the electromagnetic field for a certain period of time, the electrical characteristics of the sensitive tissues of rats have been changed to a certain extent, and some of the frequency points vary greatly. The experimental group has a significant difference compared with the control group. This paper further combines the electromagnetic field theory to analyze the possible changes in the electrical characteristics of the tissue of the rats. Mechanism.
Fourth, the effects of magnetic field, power frequency electromagnetic field and infrared radiation exposure on infrared spectrum characteristics of sensitive tissues of rats were analyzed by infrared spectroscopy. The effects of various electromagnetic field exposure on blood, nerve and reproductive system were studied. The blood, testicles and brain of rats were measured after exposure to electromagnetic field for a certain time. The infrared spectrum data of the tissue and the difference between the peak position, the peak shape and the two order derivative spectrum of the experimental group and the control group and the possible causes are analyzed in order to clarify the genetic damage loci and the effect mechanism of the electromagnetic radiation, and provide the basis for the medical protection of the electromagnetic radiation hazards.
Fifth, the effect of infrared field exposure on the disease model rats was studied. The effects of infrared field exposure on the electrical and infrared spectral characteristics of blood tissue in hyperglycemic rats were mainly used to investigate the effect of infrared exposure on Hyperglycemia Rats. The results showed that the effects of infrared exposure on Hyperglycemia Rats were discussed. The infrared field exposure was helpful to the recovery of hyperglycemic rats. The test results of electrical and infrared spectral characteristics showed that infrared exposure could help hyperglycemic rats close to normal rats.

【学位授予单位】：电子科技大学
【学位级别】：博士
【学位授予年份】：2012
【分类号】：R142

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