山东某地区产妇及新生儿脐血血清矿物质水平及孕期饮食对其影响

发布时间：2018-05-01 08:16

本文选题：矿物质 + 产妇　；参考：《环境与职业医学》2015年08期

【摘要】：[目的]通过检测山东省潍坊市某医院普通产妇血清、新生儿脐血血清中钙、镁、锌、铜和铁元素含量,了解该地区产妇及胎儿体内各元素的水平,并分析母亲孕期饮食对上述血清元素水平的影响。[方法]以2011年9月—2012年4月在山东省潍坊市某医院入院生产的产妇作为调查对象。共采集205对母血和新生儿脐血,检测血清钙、镁、锌、铜、铁元素水平;采用食物频率表收集母亲孕期的饮食信息(包括蔬菜、水果、肉类、水产品、乳制品、豆制品等的摄入情况)。采用Spearman秩相关分析血清中各个元素之间的相关性,多元logistic回归分析母脐血清中矿物质与母亲妊娠期饮食之间的相关性。[结果]产妇血清中钙、镁、锌、铜、铁元素含量的中位数分别为76.52、18.97、0.62、1.99、1.43mg/L,钙、铜元素含量低于普通人群水平;新生儿脐血血清中上述各元素含量的中位数分别为95.30、22.48、1.04、0.35、4.93 mg/L,仅铜元素含量低于普通人群水平。Spearman秩相关分析显示,产妇血清与脐血血清中钙(r=0.151,P=0.031)和铜(r=0.200,P=0.040)的含量呈正相关。logistic回归分析结果显示,孕期蔬菜、鸡蛋、豆制品摄入分别是产妇血清锌、镁、铁含量的保护因素[OR(95%CI):4.571(1.305~16.005)、11.450(1.054~124.118)、2.903(1.122~7.510)];孕期蔬菜摄入是脐血血清锌含量的保护因素[OR(95%CI):4.046(1.141~14.343)]。孕期乳制品的摄入是产妇、脐血血清锌含量的危险因素[OR(95%CI):0.281(0.084~0.944)、0.142(0.021~0.952)];而孕期蔬菜摄入是产妇血清中镁、脐血血清中铜含量的危险因素[OR(95%CI):0.242(0.069~0.848)、0.236(0.063~0.880)]。[结论]产妇血清钙、镁、锌、铜和铁含量与孕期饮食习惯有关,可通过改善孕期饮食情况来增加对各种元素的摄入。
[Abstract]:[objective] to detect the contents of calcium, magnesium, zinc, copper and iron in the serum of normal pregnant women and newborns in a hospital in Weifang, Shandong Province, and to understand the levels of elements in puerpera and fetus in this area. The effects of maternal diet during pregnancy on the serum element levels were analyzed. [methods] Maternal women who were admitted to a hospital in Weifang City, Shandong Province from September 2011 to April 2012 were investigated. A total of 205 pairs of maternal and neonatal cord blood were collected to detect the levels of calcium, magnesium, zinc, copper and iron in serum, and dietary information (including vegetables, fruits, meat, aquatic products, dairy products) during pregnancy were collected by food frequency table. Intake of soybean products, etc. Spearman rank correlation was used to analyze the correlation between each element in serum, and multiple logistic regression analysis was used to analyze the correlation between maternal umbilical serum minerals and maternal diet during pregnancy. [results] the median contents of calcium, magnesium, zinc, copper and iron in the serum of puerpera were 76.52 ~ 18.97-0.62 ~ 1.99 ~ 1.43 mg / L, respectively. The contents of calcium and copper were lower than those of the general population. The median of the above elements in cord blood serum of neonates was 95.30, 22.481.04 and 0.354.93 mg / L, respectively. Only the copper content was lower than that of the general population level. Spearman rank correlation analysis showed that, The results of logistic regression analysis showed that the intake of maternal vegetables, eggs and soy products were serum zinc and magnesium, respectively. The protective factors of iron content [ORY95CIW 4.571 1.305 ~ 16.005]; the intake of vegetables during pregnancy was the protective factor of serum zinc content in umbilical cord blood [OR95 CIW 4.0461.1411 ~ 14.343]. The intake of dairy products during pregnancy is the risk factor of serum zinc content in pregnant women, and the intake of vegetables during pregnancy is the risk factor of serum magnesium and copper content in umbilical cord blood. [conclusion] the contents of serum calcium, magnesium, zinc, copper and iron in pregnant women are related to dietary habits during pregnancy.
【作者单位】：上海交通大学公共卫生学院环境健康学系;潍坊市人民医院滨海分院;
【基金】：国家自然科学基金(编号:81172625)
【分类号】：R153.1

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