我国中老年人血清低HDL-c血症与膳食关系研究

发布时间：2018-09-01 14:55

【摘要】：目的分析我国中老年人血清低高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-c)血症与膳食的关系。方法数据来源于2010-2012年中国居民营养与健康状况监测。对我国城乡150个监测点45岁及以上居民共28 092名进行基本情况问卷调查及连续3 d的24 h膳食调查,采用直接法测定调查对象空腹血清HDL-c水平,按《中国成人血脂异常防治指南(2016年修订版)》标准判断低HDL-c血症。结果我国中老年人低HDL-c血症患病率男性高于女性(x~2=202.144,P0.001);低HDL-c血症患病率随年龄增加呈下降趋势(x~2=9.782,P=0.002);随收入增加(x~2=16.143,P0.001)和文化程度提高(x~2=95.129,P0.001)呈现上升趋势;大城市、中小城市、普通农村和贫困农村血清低HDL-c血症患病率分别为36.5%,32.4%,33.5%和34.0%,地区间差异有统计学意义(x~2=7.314,P=0.007)。城乡男性低HDL-c血症与HDL-c正常人群水果、蛋类和奶类摄入量差异均有统计学意义(均有P0.05);城乡女性低HDL-c血症与HDL-c正常人群红肉类和禽肉类摄入量差异均有统计学意义(均有P0.05)。调整其他因素后Logistic回归分析显示,低HDL-c血症与粮谷类、水果和红肉摄入有关,其OR(95%CI)值分别为1.06(1.03~1.09)、1.12(1.06~1.19)和0.91(0.89~0.93)。结论我国城乡中老年人血清低HDL-c血症患病率较高,低HDL-c血症与粮谷类、水果和红肉摄入量有关。
[Abstract]:Objective to analyze the relationship between serum low density lipoprotein cholesterol (high density lipoprotein cholesterol,HDL-c) and diet in middle aged and old people in China. Methods data were obtained from the monitoring of nutritional and health status of Chinese residents from 2010 to 2012. A total of 28 092 residents aged 45 years and above in 150 monitoring points in urban and rural areas in China were investigated with a questionnaire and a 24-hour dietary survey for 3 consecutive days. The fasting serum HDL-c levels were measured by direct method. Hypoglycemia was judged according to Chinese guidelines for the Prevention and treatment of Adult dyslipidemia (revised 2016). Results the prevalence rate of hypothyroidism in middle and old people in China was higher than that in female (x2 / 2 / 202.144 / P0.001), and the prevalence rate of low HDL-c was decreasing with the increase of age (x2 / 2 / 9.782 / 0 / 2), increasing with the increase of income (x2 / 2/ 16.143 / P ~ (0.001) and educational level (\ {x\} 295.129P0.001\}), while in big cities, small and medium-sized cities, it showed an increasing trend. The prevalence rate of serum hypothyroidism was 36.5% and 34.0% in common rural and poor rural areas, respectively. There were significant differences in intake of fruit, eggs and milk between urban and rural men with hypoglycemia and HDL-c (P0.05), and between urban and rural women with hypoHDL-c and normal HDL-c (P0.05). After adjusting for other factors, Logistic regression analysis showed that hypoglycemia was related to the intake of cereals, fruits and red meat, and its OR (95%CI) values were 1.06 (1.031.09) 1.12 (1.061.19) and 0.91 (0.890.93), respectively. Conclusion the prevalence rate of serum hypothyroidism in urban and rural middle and old people is high. Low HDL-c is related to the intake of grain, fruit and red meat.
【作者单位】：中国疾病预防控制中心营养与健康所;北京市疾病预防控制中心中心实验室;
【基金】：国家卫生计生委(原卫生部)医改重大专项[中国居民营养与健康状况监测(2010-2013年)]
【分类号】：R151.41

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