重庆某三甲教学医院住院患者及医务人员丙肝病毒患病率调查

发布时间：2018-09-19 08:59

【摘要】：目的:慢性丙型肝炎通常为隐匿感染,容易进展至肝硬化、肝癌,最终危及生命,目前我国对医院患者及医务工作者感染丙肝流行状况较少,故调查住院病人、医务人员患病率、感染特点及分析两者感染相关性,对预防院内交叉感染、控制感染进展有重要意义。方法:回顾性收集我院2014年住院病人丙肝血清学筛查结果和进行我院2015年全院参加体检职工丙肝血清学指标检测,然后分析高危患者及高危科室医务人员之间是否存在一定相关性,使用卡方检验对数据进行分析。结果:在参与筛查人数30627住院患者中丙肝抗体阳性率为0.95%,男性高于女性,内科高于外科,基因分型主要为3型,治疗率不高;在全院职工调查当中,参与筛查人数1942人,其中抗HCV阳性率0.15%。结论:我院住院患者丙肝病毒患病率与全国总体水平相似,医务人员患病率不高,我院住院患者丙肝感染患者无明显聚集与爆发,医务人员在操作流程可安心工作,不必过度担心被感染风险。
[Abstract]:Objective: chronic hepatitis C is usually concealed infection, easy to progress to liver cirrhosis, liver cancer, and ultimately life-threatening. At present, the prevalence of hepatitis C infection among hospital patients and medical workers in China is relatively low, so the inpatients were investigated. The prevalence rate, infection characteristics and the correlation between the two infections are of great significance for the prevention of nosocomial cross infection and the control of infection progression. Methods: the results of serum screening for hepatitis C in inpatients in our hospital in 2014 were collected retrospectively, and the serum levels of hepatitis C in the staff of our hospital in 2015 were detected. Then the correlation between high-risk patients and high-risk department medical staff was analyzed by chi-square test. Results: the positive rate of HCV antibody was 0.95in the 30627 inpatients who participated in the screening, male was higher than female, internal medicine was higher than surgery, genotyping was mainly type 3, treatment rate was not high. The positive rate of anti HCV was 0. 15%. Conclusion: the prevalence rate of hepatitis C virus in inpatients in our hospital is similar to that in the whole country, the prevalence rate of medical staff is not high, there is no obvious aggregation and outbreak of hepatitis C infection in inpatients in our hospital, and the medical staff can work safely in the operation process. Don't worry too much about the risk of infection.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R512.63;R181.3

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