呼伦贝尔地区不同民族小学生血脂状况分析

发布时间：2018-10-09 08:25

【摘要】：目的了解内蒙古呼伦贝尔地区蒙族、鄂温克族、汉族小学生的血脂水平,为建立少数民族地区小学生血脂水平的参考区间提供参考依据。方法采用整群抽样方法,于2009—2011年抽取呼伦贝尔市民族小学和牙克石市建设小学8~14岁小学生1 723名,应用OLYMPUS公司生产的AU5421全自动生化分析仪检测空腹血清胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1(APOA1)、载脂蛋白B(APOB)水平。取TC及LDL-C第75及第90百分位点作为临界脂蛋白水平及高脂蛋白浓度标准,取TG第90百分位点作为高三酰甘油血症浓度,取第5百分位点作为HDL-C的参考区间下限,取APOA1,APOB的95%可信区间建立呼伦贝尔地区3个民族小学生血脂正常参考区间。结果汉族除LDL-C与鄂温克族差异无统计学意义(t=0.575,P0.05)外,其他5项血脂水平(TC,TG,HDL-C,APOA1,APOB)与蒙古族和鄂温克族差异均有统计学意义(t/F值分别为20.256,85.047,15.604,310.143,39.947,P值均0.01);蒙古族和鄂温克族除TC,TG差异无统计学意义(t值分别为0.491,0.643,P值均0.05)外,其他4项血脂水平差异均有统计学意义(t值分别为2.911,2.548,5.161,3.417,P值均0.01);蒙古族、汉族男、女生组除TC外,其他项目血脂水平(TC,TG,HDL,APOA1)差异均有统计学意义(t蒙古值分别为4.619,3.690,3.527,4.409,4.130,t汉值分别为4.856,2.607,2.035,2.967,2.525,P值均0.01),鄂温克族男、女除LDL-C、APOB以外,其他4项血脂水平差异均有统计学意义(t值分别为3.741,4.230,2.106,2.136,P值均0.01)。结论调查建立了蒙、鄂、汉3个民族小学生血脂各自的参考区间,可为儿童心血管疾病的早期预防工作提供基础资料。
[Abstract]:Objective to study the blood lipid level of Mongolian, Ewenki and Han pupils in Hulunbeir area, Inner Mongolia, and to provide reference basis for establishing reference range of lipid level of primary school students in minority areas. Methods using cluster sampling method, 1 723 primary school students aged 814 years old in Hulunbeir ethnic primary school and Yakeshi construction primary school were selected from 2009 to 2011. The fasting serum (TC), triacylglycerol (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), apolipoprotein A1 (APOA1) and apolipoprotein B (APOB) were measured by AU5421 automatic biochemical analyzer made by OLYMPUS. The 75 and 90 percentiles of TC and LDL-C were taken as the critical lipoprotein level and high lipoprotein concentration standard, the 90th percentile of TG as the hypertriglyceridemia concentration, and the 5th percentile as the lower limit of the reference range of HDL-C. The 95% confidence interval of APOA1,APOB was used to establish the normal reference interval of serum lipids in three ethnic pupils in Hulunbeir area. Results there was no significant difference between LDL-C and Ewenki in Han nationality (P 0.05). The other five items of blood lipid level (TC,TG,HDL-C,APOA1,APOB) were significantly different from those of Mongolian and Ewenki (t / F = 20.256U 85.047N 15.604310.143n 39.947 P, respectively), but there was no significant difference between Mongolian nationality and Ewenki nationality except TC,TG (t = 0.4910.643P, P = 0.4910.643P, respectively). There were significant differences in the other four items of serum lipids (t = 2.9111.548, 5.161and 3.417P, respectively), except for the Mongolian, Han nationality boys and girls, except TC. There were significant differences in blood lipid level (TC,TG,HDL,APOA1) between other items (t Mongolia was 4.619 3.690, 3.527, 4.409, 4.130, P = 4.856, 2.6072.035, 2.96775, 2.525, P, respectively), and there were significant differences between Ewenki men and women except LDL-C,APOB (t = 3.741, 4.2302.106, 2.136P, respectively). Conclusion the investigation has established the reference interval of serum lipids in primary school students of Mongolian, Hubei and Han nationalities, which can provide basic data for early prevention of cardiovascular diseases in children.
【作者单位】：内蒙古林业总医院;
【基金】：内蒙古民族大学科研资助项目(DX2008102)
【分类号】：R179

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