某沿海城市烤鱼片中河豚毒素的含量分析及人群膳食暴露评价

发布时间：2018-10-09 20:44

【摘要】：目的了解某沿海城市生产和流通环节烤鱼片中河豚毒素的污染状况,评价烤鱼片中河豚毒素的人群膳食暴露风险,为消费者安全消费和企业规范生产以及监管部门的风险预警提供依据。方法采用分层随机抽样的方法,采集烤鱼片样本,按照酶联免疫的方法,进行河豚毒素的检测。运用急性暴露评估模型,评价潜在的风险。结果某沿海城市烤鱼片中河豚毒素阳性检出率为40%,含量范围为0.10 mg/kg~4.22 mg/kg,毒力范围为0.45 MU/g~19.18 MU/g,无毒级别样本占98.82%。儿童、青少年、成年人和老年人的急性风险指数均100%。结论某沿海城市烤鱼片中存在河豚毒素的污染,但绝大多数为无毒级别,总体处在安全水平。烤鱼片中河豚毒素的人群急性膳食暴露风险较高,儿童、青少年的急性膳食暴露风险高于成年人和老年人,同年龄段女性的急性膳食暴露风险略高于男性。按照检样中河豚毒素含量评估,成年人、老年人一次摄入低于45 g,儿童、青少年一次摄入量低于15g的烤鱼片时,其急性膳食暴露水平处在可接受的安全状态。
[Abstract]:Objective to investigate the status of tetrodotoxin pollution in roasted fish tablets in a coastal city and to evaluate the dietary exposure risk of tetrodotoxin in roasted fish tablets. It provides the basis for consumer safety consumption and enterprise standard production and risk warning of supervision department. Methods A stratified random sampling method was used to detect tetrodotoxin by enzyme linked immunosorbent assay (Elisa). Use acute exposure assessment model to evaluate potential risks. Results the positive rate of tetrodotoxin in roasted fish tablets of a coastal city was 40. The virulence range of tetrodotoxin was 0. 10 mg/kg~4.22 mg/kg,. The nontoxic grade sample of 0. 45 MU/g~19.18 MU/g, accounted for 98. 82% of tetrodotoxin. The acute risk index for children, adolescents, adults and the elderly was 100. Conclusion there is tetrodotoxin pollution in roasted fish slices in a coastal city, but most of them are nontoxic, and they are generally safe. The risk of acute dietary exposure of children and adolescents was higher than that of adults and the elderly, and that of women of the same age was slightly higher than that of men. According to the evaluation of tetrodotoxin content in the samples, the acute dietary exposure level of adults and the elderly was in an acceptable safe state when the intake of roasted fish was less than 45 g at a time, and the intake of children and adolescents was less than 15 g at a time.
【作者单位】：烟台市疾病预防控制中心食品营养与学生保健科;
【分类号】：R155.5

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