一起埃可30型病毒引起的学校病毒性脑膜炎暴发疫情分析

发布时间：2018-10-21 13:39

【摘要】：目的分析一起埃可30型病毒引起的学校病毒性脑膜炎暴发疫情的流行病学特征及可能的危险因素,为制定预防控制措施提供科学依据。方法采用现场流行病学调查收集病例情况和可能的传播途径等信息,采集相关标本进行PCR核酸检测,采用1∶2匹配病例对照研究方法探索可能的危险因素。结果共报告103例病例,罹患率4.6%,男女性别比2.03∶1,病例主要集中在三年级(72/103)。病例咽拭子、肛拭子肠道通用病毒RT-PCR检测81.5%(22/27)为阳性,其中7例PCR序列分析确定为埃可30型病毒。结论此次病毒性脑膜炎暴发疫情是由埃可30型病毒引起的,加强学校传染病防控知识培训、卫生宣教、晨检、因病缺课病因追查、登记和报告、病例隔离和疫点消毒工作对控制疫情十分重要。
[Abstract]:Objective to analyze the epidemiological characteristics and possible risk factors of a school viral meningitis outbreak caused by Echo 30 virus, and to provide scientific basis for making prevention and control measures. Methods the information of cases and possible ways of transmission were collected by field epidemiological investigation. PCR nucleic acid was detected in relevant samples. The 1:2 matched case-control study was used to explore the possible risk factors. Results 103 cases were reported, the attack rate was 4.6%, the ratio of male to female was 2.03: 1. The cases were mainly in the third grade (72 / 103). In throat swabs and anal swabs, 81.5% (22 / 27) of the cases were positive for enterovirus RT-PCR, among which 7 cases were identified as EK30 virus by PCR sequence analysis. Conclusion the outbreak of viral meningitis is caused by EK30 virus. We should strengthen the knowledge training of infectious disease prevention and control, health education, morning examination, tracing, registration and report of the disease absent from school. Isolation of cases and disinfection of epidemic spots are very important for the control of epidemic situation.
【作者单位】：江阴市疾病预防控制中心;江阴市徐霞客医院;
【分类号】：R725.1;R181.3

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