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学龄双生子儿童身体围度与宽度指标的遗传学分析

发布时间:2018-12-18 12:25
【摘要】:为探讨遗传和环境因素对学龄双生子儿童身体围度及宽度等体格指标的影响,对351对6~12岁双生子儿童身高、胸围、腰围、臀围、肩宽、骨盆宽指标进行测量,计算各指标的相关指数。应用Mx软件拟合最佳结构方程模型计算各指标遗传度,分析年龄与性别的作用。结果发现,各指标拟合的最佳模型均为ACES,各测量指标的年龄方差较大(0.21~0.76),衍生指数中除腰臀比(女0.15,男0.05)外几乎均不存在年龄方差;各指标的共同环境方差变异较大(0.00~0.53);衍生指数的特殊环境因素方差(0.09~0.25)总体上高于测量指标(0.01~0.09)。校正年龄后,各指标遗传度为身高(女63%,男59%)、胸围(女84%,男88%)、身高胸围指数(女87%,男55%)、腰围(女46%,男64%)、臀围(女61%,男61%)、腰臀比(女44%,男44%)、肩宽(女78%,男78%)、骨盆宽(女62%,男62%)、身高肩宽指数(女40%,男40%)、身高骨盆宽指数(女35%,男48%)、肩宽骨盆宽指数(女24%,男24%)。结果表明学龄双生子儿童身高、胸围、身高胸围指数、臀围、肩宽、骨盆宽主要受遗传因素影响;腰臀比、身高肩宽指数、身高骨盆宽指数及肩宽骨盆宽指数受环境因素影响更大;遗传与环境因素对身高胸围指数、腰围指标的影响可能存在一定性别差异;年龄对学龄双生子儿童身体围度及宽度相关指数的影响较小。
[Abstract]:In order to investigate the effect of genetic and environmental factors on the body circumference and width of school-age twin children, the height, chest circumference, waist circumference, hip circumference, shoulder width and pelvic width of 351 children aged 12 years old were measured. Calculate the relative index of each index. The heritability of each index was calculated by fitting the best structural equation model with Mx software, and the effect of age and sex was analyzed. The results showed that the best fitting model of each index was that the age variance of ACES, was larger (0.21% 0.76), and that there was almost no age variance in the derived index except waist hip ratio (female 0.15, male 0. 05). The variation of common environmental variance of each index was greater (0.000.53), and the variance of special environmental factor of derivative index (0.090.25) was higher than that of measurement index (0.01n.09). After adjusting for age, the heritability of the indexes were height (female 63, male 59%), chest circumference (female 84, male 88%), height chest circumference index (female 87, male 55%), waist circumference (female 46, male 64%), hip circumference (female 61 1, male 61 1%). Waist to hip ratio (female 44, male 44%), shoulder width (female 78, male 78%), pelvis width (female 62, male 62%), height shoulder width index (female 40, male 40%), height pelvic width index (35 female, 48% male), waist to hip ratio (female 44, male 44%), pelvis width (female 62, male 62%), height and shoulder width index (female 40, male 40%), height pelvis width index (female 35, male 48%), Shoulder width and pelvis width index (female 24%, male 24%). The results showed that height, chest circumference, height chest circumference index, hip circumference, shoulder width and pelvic width were mainly affected by genetic factors. Waist to hip ratio, height shoulder width index, height pelvis width index and shoulder width pelvis width index are more affected by environmental factors, genetic and environmental factors may have some gender differences in height chest circumference index and waist circumference index. Age had little effect on body circumference and width related index of school age twin children.
【作者单位】: 内蒙古师范大学生命科学与技术学院;
【基金】:国家自然科学基金资助项目(31260265;30960167)
【分类号】:R179

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