银川吴忠两市儿童青少年维生素D营养状况
发布时间:2019-01-04 20:19
【摘要】:目的了解宁夏银川、吴忠两市儿童青少年维生素D营养状况,为预防儿童青少年维生素D不足与缺乏提供合理依据。方法在银川市2区和吴忠市随机抽取小学、初中和高中,采用分层整群抽样的方法抽取班级。排除佝偻病、克罗恩病、心血管疾病及肝肾疾病患者,以及近3月内服用过维生素D补充剂的儿童青少年,共选取7~18岁对象2 167名。采集研究对象空腹静脉血,采用酶联免疫吸附法(ELISA法)测定其血清25(OH)D的浓度。结果银川、吴忠两市儿童青少年血清25(OH)D浓度中位数为51.46 nmol/L,四分位数间距为61.46 nmol/L,维生素D充足、不足、缺乏检出率分别为51.9%,14.1%,34.0%。不足检出率以7岁最高,8~13岁随着年龄的增长呈升高趋势,至14岁开始逐渐降低。7~18岁各年龄组儿童青少年缺乏检出率依次为31.9%,27.9%,20.8%,30.1%,36.7%,2.4%,29.8%,32.3%,35.3%,47.5%,37.3%,32.8%,各年龄组均较高。不同年龄组间维生素D水平及缺乏检出率比较,差异均有统计学意义(H=43.086,P0.01;χ~2=11.156,P=0.001)。回、汉族儿童青少年维生素D水平、不足与缺乏检出率比较,差异均无统计学意义(P值均0.05)。结论银川、吴忠两市7~18岁儿童青少年维生素D水平较低,维生素D缺乏检出率较高;随年龄增长,儿童青少年血清维生素D水平逐渐降低,不足、缺乏检出率升高。
[Abstract]:Objective to investigate the vitamin D nutritional status of children and adolescents in Yinchuan and Wu Zhong in Ningxia, and to provide reasonable basis for preventing deficiency and deficiency of vitamin D in children and adolescents. Methods the primary, middle and senior middle schools were randomly selected from Yinchuan District 2 and Wuzhong City, and the classes were sampled by stratified cluster sampling. Patients with rickets, Crohn's disease, cardiovascular diseases, liver and kidney diseases, and children and adolescents who had taken vitamin D supplements in recent three months were excluded. A total of 2,167 subjects aged 718 years were selected. Fasting venous blood was collected and the serum concentration of 25 (OH) D was determined by enzyme linked immunosorbent assay (ELISA). Results the median concentration of 25 (OH) D in serum of children and adolescents in Yinchuan and Wu Zhong cities was 51.46 nmol/L, / quartile interval. The interval of vitamin D was 61.46 nmol/L,. The deficiency rate was 51.9 nmol/L, and 14.1g, respectively. 34.0. The highest detection rate was in the age of 7, and the rate of deficiency in the age of 813 increased with the increase of age, and gradually decreased at the age of 14. The detectable rate of the deficiency of children and adolescents in the age group of 718 years was 31.927. 9% and 20.8% 30.1yr, respectively. 36.7and 2.4and 29.8m, 32.33.35 and 37.5, and 37.3 and 32.8. all the age groups are higher than the other three, and they are 37.3% and 37.3%, 37.3%, 37.3%, 37.3%, 37.3% and 37.3%, respectively. The levels of vitamin D and the prevalence of vitamin D deficiency were significantly different among different age groups (P 0.01; 蠂 2 11.156 P 0.001). There was no significant difference in vitamin D levels between children and adolescents of Han nationality (P < 0.05). Conclusion the levels of vitamin D and vitamin D deficiency in children and adolescents aged 7 ~ 18 years in Yinchuan and Wu Zhong are lower and the detection rate of vitamin D deficiency is higher, and the serum vitamin D level of children and adolescents decreases gradually with the increase of age.
【作者单位】: 宁夏医科大学公共卫生与管理学院;
【分类号】:R179
[Abstract]:Objective to investigate the vitamin D nutritional status of children and adolescents in Yinchuan and Wu Zhong in Ningxia, and to provide reasonable basis for preventing deficiency and deficiency of vitamin D in children and adolescents. Methods the primary, middle and senior middle schools were randomly selected from Yinchuan District 2 and Wuzhong City, and the classes were sampled by stratified cluster sampling. Patients with rickets, Crohn's disease, cardiovascular diseases, liver and kidney diseases, and children and adolescents who had taken vitamin D supplements in recent three months were excluded. A total of 2,167 subjects aged 718 years were selected. Fasting venous blood was collected and the serum concentration of 25 (OH) D was determined by enzyme linked immunosorbent assay (ELISA). Results the median concentration of 25 (OH) D in serum of children and adolescents in Yinchuan and Wu Zhong cities was 51.46 nmol/L, / quartile interval. The interval of vitamin D was 61.46 nmol/L,. The deficiency rate was 51.9 nmol/L, and 14.1g, respectively. 34.0. The highest detection rate was in the age of 7, and the rate of deficiency in the age of 813 increased with the increase of age, and gradually decreased at the age of 14. The detectable rate of the deficiency of children and adolescents in the age group of 718 years was 31.927. 9% and 20.8% 30.1yr, respectively. 36.7and 2.4and 29.8m, 32.33.35 and 37.5, and 37.3 and 32.8. all the age groups are higher than the other three, and they are 37.3% and 37.3%, 37.3%, 37.3%, 37.3%, 37.3% and 37.3%, respectively. The levels of vitamin D and the prevalence of vitamin D deficiency were significantly different among different age groups (P 0.01; 蠂 2 11.156 P 0.001). There was no significant difference in vitamin D levels between children and adolescents of Han nationality (P < 0.05). Conclusion the levels of vitamin D and vitamin D deficiency in children and adolescents aged 7 ~ 18 years in Yinchuan and Wu Zhong are lower and the detection rate of vitamin D deficiency is higher, and the serum vitamin D level of children and adolescents decreases gradually with the increase of age.
【作者单位】: 宁夏医科大学公共卫生与管理学院;
【分类号】:R179
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