期待与清宫治疗中期引产后宫内妊娠物残留的预后及并发症（英文）
发布时间：2019-03-22 08:42
【摘要】：目的探讨期待治疗和清宫治疗中期引产后宫内妊娠物残留的预后及治疗后相关并发症的风险因素。方法回顾性收集2014 年1 月~2015 年12 月在南方医院中期引产后行期待和清宫治疗宫内妊娠物残留的270 例患者的临床资料,采用Mann-Whitney U检验和卡方检验比较两种治疗方法的阴道流血时间和月经复潮时间,建立二分类logistics回归模型,用双变量和多变量分析治疗后相关并发症发生的风险因素。结果期待治疗组阴道流血时间显著长于清宫治疗组(P=0.005),但阴道流血时间超过42 d者显著少于清宫组(P=0.040);两组月经复潮时间(P=0.287)以及月经复潮时间超过60 d者差异无统计学意义(P=0.783)。二分类logistics回归分析显示,清宫组并发症发生风险显著高于期待治疗组(优势比=10.60,95%置信区间2.36~47.66,P=0.002)。在控制年龄、孕产次、孕周、子宫手术史、引产指征、引产方法及引产排胎时间等混杂因素后,清宫组并发症发生风险仍然显著高于期待治疗组(优势比=18.26,95%置信区间3.57~93.42,P0.001)。结论期待治疗宫内妊娠物残留可能会延长阴道流血时间,但可减少阴道流血时间超过42 d的发生率,而且不引起明显的治疗后并发症。
[Abstract]:Objective to investigate the prognosis and risk factors of complications related to intrauterine pregnancy after mid-term induction of labor. Methods from January 2014 to December 2015, the clinical data of 270 cases of intrauterine pregnancy residue treated by expectation and palace cleaning after induction of labor in Southern Hospital from January 2014 to December 2015 were retrospectively collected. Mann-Whitney U test and chi square test were used to compare the vaginal bleeding time and menstruation recovery time between the two treatment methods. A binary logistics regression model was established and the risk factors of related complications after treatment were analyzed by bivariate and multivariate analysis. Results the duration of vaginal bleeding in the prospective treatment group was significantly longer than that in the Qinggong treatment group (P < 0.005), but the vaginal bleeding time over 42 days in the treatment group was significantly shorter than that in the Qinggong group (P < 0.040). There was no significant difference between the two groups in menorrhagia time (P < 0. 287) and menstruation recovery time more than 60 days (P = 0. 783). The binary logistics regression analysis showed that the risk of complications in the Qinggong group was significantly higher than that in the prospective treatment group (odds ratio = 10.60, 95% confidence interval 2.36, 47.66, P < 0.002). After controlling confounding factors such as age, gestational time, gestational week, history of uterine surgery, indication of induced labor, method of induced labor and time of abortion, The risk of complications in the Qinggong group was still significantly higher than that in the prospective treatment group (odds ratio = 18.26, 95% confidence interval 3.5793.42, P0.001). Conclusion expectant treatment of intrauterine pregnancy residue may prolong vaginal bleeding time, but can reduce the incidence of vaginal bleeding more than 42 days, and does not cause obvious post-treatment complications.
【作者单位】： 南方医科大学南方医院妇产科;南方医科大学公共卫生学院生物统计学系;耶鲁大学公共卫生学院生物统计学系;
【分类号】：R169.42
本文编号：2445443
[Abstract]:Objective to investigate the prognosis and risk factors of complications related to intrauterine pregnancy after mid-term induction of labor. Methods from January 2014 to December 2015, the clinical data of 270 cases of intrauterine pregnancy residue treated by expectation and palace cleaning after induction of labor in Southern Hospital from January 2014 to December 2015 were retrospectively collected. Mann-Whitney U test and chi square test were used to compare the vaginal bleeding time and menstruation recovery time between the two treatment methods. A binary logistics regression model was established and the risk factors of related complications after treatment were analyzed by bivariate and multivariate analysis. Results the duration of vaginal bleeding in the prospective treatment group was significantly longer than that in the Qinggong treatment group (P < 0.005), but the vaginal bleeding time over 42 days in the treatment group was significantly shorter than that in the Qinggong group (P < 0.040). There was no significant difference between the two groups in menorrhagia time (P < 0. 287) and menstruation recovery time more than 60 days (P = 0. 783). The binary logistics regression analysis showed that the risk of complications in the Qinggong group was significantly higher than that in the prospective treatment group (odds ratio = 10.60, 95% confidence interval 2.36, 47.66, P < 0.002). After controlling confounding factors such as age, gestational time, gestational week, history of uterine surgery, indication of induced labor, method of induced labor and time of abortion, The risk of complications in the Qinggong group was still significantly higher than that in the prospective treatment group (odds ratio = 18.26, 95% confidence interval 3.5793.42, P0.001). Conclusion expectant treatment of intrauterine pregnancy residue may prolong vaginal bleeding time, but can reduce the incidence of vaginal bleeding more than 42 days, and does not cause obvious post-treatment complications.
【作者单位】： 南方医科大学南方医院妇产科;南方医科大学公共卫生学院生物统计学系;耶鲁大学公共卫生学院生物统计学系;
【分类号】：R169.42
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