急性有机磷农药中毒患者血液流变学指标变化的意义

发布时间：2018-06-26 19:14

本文选题：有机磷农药 + 中毒　；参考：《中国急救医学》2005年02期

【摘要】：目的探讨急性有机磷农药中毒(AOPP)患者血液流变学指标改变的临床意义。方法选择了30例急性有机磷农药中毒患者,按入院时中毒程度分为轻度中毒组和中、重度中毒两组,在入院第1天和第7天分别采血进行血液流变学指标的检测(其中包括全血高切黏度、全血低切黏度、血浆黏度、血浆纤维蛋白原、血细胞比容及红细胞沉降率),与健康对照组比较,中毒相同时间两个中毒组间的比较,中毒组内第1天和第7天比较。结果中毒第1天,中毒组与健康对照组比较,各项均明显增高,差异显著(P005和P001)。中毒第7天,中毒组与健康对照组比较,轻度中毒组基本恢复正常(P005),而中、重度中毒组恢复缓慢,6项中仍有3项显著增高(P005);两个中毒组间比较,中、重度中毒组仍有5项高于轻度中毒组,3项差异显著(P005)。结论AOPP患者血液流变学指标的改变与中毒程度有关,动态观察血液流变学指标的改变,对判定中毒程度和指导治疗有重要意义。
[Abstract]:Objective to investigate the clinical significance of changes of hemorheological indexes in patients with acute organophosphorus pesticide poisoning (AOPP). Methods 30 patients with acute organophosphorus pesticide poisoning were selected and divided into mild poisoning group and two groups according to the degree of intoxication at admission. The blood rheology indexes were detected in first days and seventh days, respectively. The total blood viscosity, blood viscosity, plasma viscosity, plasma fibrinogen, blood cell specific volume and erythrocyte sedimentation rate were compared with those of the healthy control group, compared with the two poisoning groups at the same time, first days and seventh days in the poisoning group. The results were first days, the poisoning group and the healthy control group were all significantly increased. The difference was significant (P005 and P001). Seventh days of intoxication, compared with the healthy control group, the mild poisoning group was basically recovered (P005), but in the moderate, severe poisoning group, the recovery was slow, and there were 3 significant increases in the 6 items (P005); in the two poisoning groups, 5 items were still higher than the mild poisoning group, and the 3 items were significantly different (P005). Conclusion AOPP The change of blood rheology index is related to the degree of poisoning. It is of great significance to determine the changes of hemorheological indexes dynamically and to judge the degree of poisoning and guide the treatment.
【作者单位】：新乡医学院第一附属医院检验科
【基金】：河南省科研基金资助项目(No0124170680)
【分类号】：R826

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