中西医结合治疗小儿原发性肾病综合征67例疗效观察

发布时间：2018-05-26 18:03

本文选题：原发性肾病综合征 + 中西医结合疗法　；参考：《新中医》2009年08期

【摘要】：目的:观察中西医结合治疗小儿原发性肾病综合征(PNS)的临床疗效。方法:将67例PNS患儿随机分为治疗组34例、对照组33例。均给予激素及免疫抑制剂、抗凝、钙剂等西药对症治疗,治疗组在此基础上加用中医药辨证施治。治疗前后分别检测血清甘油三酯(TG)、胆固醇(TC)、血肌酐、血黏度、血小板聚集率、24h尿蛋白定量。结果:治疗组完全、基本、部分缓解率及无效率,与对照组比较,差异有显著性意义(P0.05)。所有入选病例随访1～5年,治疗组复发率也低于对照组,2组比较,差异有显著性意义(P0.05)。2组治疗后TG、TC、血黏度、血小板聚集率、24h蛋白尿定量均明显下降,与治疗前比较,差异有显著性意义(P0.05)。治疗组下降更为显著,与对照组比较,差异有显著性意义(P0.05)。结论:中西医结合治疗小儿PNS疗效确切,较之单纯西药治疗有明显优势。
[Abstract]:Objective: to observe the clinical effect of integrated traditional Chinese and western medicine on children with primary nephrotic syndrome (PNS). Methods: 67 children with PNS were randomly divided into treatment group (n = 34) and control group (n = 33). Hormone and immunosuppressant, anticoagulant, calcium and other western medicine were given for symptomatic treatment. Before and after treatment, serum triglyceride (TG), cholesterol (TC), serum creatinine (SCR), blood viscosity, platelet aggregation rate and 24 hours urine protein were measured. Results: the complete, basic, partial remission rate and ineffective rate in the treatment group were significantly different from those in the control group (P 0.05). All the patients were followed up for 1 ~ 5 years. The recurrence rate of the treatment group was also lower than that of the control group. There was a significant difference between the two groups. The TGV TC, blood viscosity, platelet aggregation rate and 24 hours proteinuria were significantly decreased in the treatment group, compared with those before the treatment. The difference was significant (P 0.05). The decrease was more significant in the treatment group than in the control group, and the difference was significant (P 0.05). Conclusion: combination of traditional Chinese and western medicine is more effective than western medicine in the treatment of PNS in children.
【作者单位】：深圳市宝安区中医院;
【分类号】：R726.9

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